The PTM profiling of CTCF reveals the regulation of 3D ... - Nature
2024年4月1日 · CCCTC-binding factor (CTCF), a ubiquitously expressed and highly conserved protein, is known to play a critical role in chromatin structure. Post-translational modifications …
CTCF and Its Partners: Shaper of 3D Genome during Development
2022年8月2日 · Post-translational modification (PTM) enzymes are CTCF’s partners. (A) CTCF is regulated by three types of PTM, namely, PARylation, SUMOylation, and phosphorylation. (B) …
丁俊军实验室 - Sun Yat-sen University
近日，丁俊军实验室在Nature Communications发表了题为 The PTM profiling of CTCF reveals the regulation of 3D chromatin structure by O-GlcNAcylation 的研究成果。 该研究...
CCCTC-binding factor (CTCF), a ubiquitously expressed and highly conserved protein, is known to play a critical role in chromatin structure. Post-translational modifications (PTMs) diversify the...
The PTM profiling of CTCF reveals the regulation of 3D chromatin ...
CTCF, which is known to play critical role in chromatin structure, undergoes post-translational modifications (PTMs). In this research, O-GlcNAcylation was found to inhibit CTCF binding, …
The PTM profiling of CTCF reveals the regulation of 3D chromatin ...
2024年4月1日 · CCCTC-binding factor (CTCF), a ubiquitously expressed and highly conserved protein, is known to play a critical role in chromatin structure. Post-translational modifications …
CTCF 的 PTM 分析揭示了 O-GlcNAc 酰化对 3D 染色质结构的调 …
在这项研究中，我们揭示了 ctcf 的 ptm 分析，并证明 ctcf 可以被 o-glcnac 酰化和精氨酸甲基化。 从功能上讲，我们证明 O-GlcNAc 酰化可抑制 CTCF 与染色质的结合。
The PTM profiling of CTCF reveals the regulation of 3D chromatin ...
CCCTC-binding factor (CTCF), a ubiquitously expressed and highly conserved protein, is known to play a critical role in chromatin structure. Post-translational modifications (PTMs) diversify …
CTCF-Mediated Human 3D Genome Architecture Reveals ... - Cell …
We applied an advanced chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) strategy to comprehensively map higher-order chromosome folding and specific chromatin …
Exploration of CTCF post-translation modifications uncovers ... - PubMed
2019年1月24日 · Although previous studies sought to explain CTCF multivalency based on sequence composition of binding sites, few examined how CTCF post-translational …