2024年12月24日 · CUX1 (Cut Like Homeobox 1) is a Protein Coding gene. Diseases associated with CUX1 include Global Developmental Delay With Or Without Impaired Intellectual …

CUX1 is an animal gene. The name stands for Cut like homeobox 1. The term "cut" derives from the "cut wing" phenotype observed in a mutant of Drosophila melanogaster. [1] In mammals, a …

2016年12月2日 · CUX1 is located at chromosome 7q22.1; -7/del(7q) involving CUX1 locus are common abnormalities in myelodysplastic syndromes (MDS). Mutations and loss of …

2023年8月30日 · We analyze brain CUX1 expression and susceptibility to epilepsy in Cux1+/− mice. We describe 34 individuals, from which 30 were unrelated, with 26 different null and four …

2021年4月30日 · Cut-like homeobox 1 (CUX1) is a haploinsufficient tumor suppressor commonly inactivated in acute myeloid leukemia and high-risk myelodysplasia.

By alternative transcriptional initiation and/or proteolytic processing, CUX1 generates several short isoforms that possess distinct DNA-binding capacity and transcriptional activities …

2014年9月5日 · Nature Reviews Cancer - CUT-like homeobox 1 (CUX1) is a homeobox gene that is implicated in both tumour suppression and progression. What are the functions of the CUX1 …

2024年5月12日 · CUX1 is a homeodomain-containing transcription factor that is essential for the development and differentiation of multiple tissues. CUX1 is recurrently mutated or deleted in …

Cux1 is a tumor suppressor and inactivating CUX1 mutations promote tumorigenesis. Our results provide the first evidence that polymorphisms of the CUX1 gene may be associated with …

数据库分析结直肠癌患者的癌组织和癌旁组织中cux1的表达情况,通过实时荧光定量pcr(qrtGpcr)检测 cux1在结直肠癌组织中的表达情况;利用gepia数据库分析cux1表达对结直肠癌患者术后总 …