The chemokine (C-X-C motif) ligand 1 (CXCL1) is a small peptide belonging to the CXC chemokine family that acts as a chemoattractant for several immune cells, especially neutrophils [5] [6] or other non-hematopoietic cells to the site of injury or infection and plays an important role in regulation of immune and inflammatory responses. It was ...

2024年12月24日 · CXCL1 (C-X-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CXCL1 include Tonsillitis and Bacterial Meningitis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and GPCR downstream signalling.

2025年3月8日 · This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a …

CXCL1 （英語： Chemokine (C-X-C motif) ligand 1）是一小分子的 细胞因子 属于CXC 趋化因子 家族 [1]。 又被称作 生长调节致癌基因α (Growth-regulated oncogene alpha, GROα) [1][2][3]。 趋化因子CXCL1是由 巨噬细胞， 中性粒细胞 和 上皮细胞 表达的 [4][5]。 趋化因子CXCL1对中性粒细胞有细胞趋化作用 [1]。 CXCL1结合到趋化因子受体 CXCR2 上而起细胞趋化作用 [6]。 人类的CXCL1与许多CXC类的趋化因子基因相邻聚集在第四染色体上 [7] 。 CXCL1的主要作用包括 …

2022年1月12日 · CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines involved in the development of many inflammatory diseases. It activates CXCR2 and, at high levels, CXCR1. The expression of <i>CXCL1</i> is elevated in inflammatory reactions and also has important functio</span> …

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth fa ctor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils.

CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines involved in the development of many inflammatory diseases. It activates CXCR2 and, at high levels, CXCR1.

2025年2月8日 · The chemokine Cxcl1 is a novel target gene of parathyroid hormone (PTH)/PTH-related protein in committed osteoblasts. These findings suggest a neuroprotective role for CXCL1 during the course of autoimmune demyelination

2023年7月1日 · CXCL1, known as growth related oncogene, can be expressed in many immune cells and neurons. The main function of CXCL1 is recruitment of immunocytes, especially neutrophils [ 8 ].

2024年2月5日 · This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a …