Chemokine receptor CXCR3 is a Gα i protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. There …

CXCR3 is present in tumor and immune cells, and its two variants, CXCR3-A and CXCR3-B, have different molecular characteristics and can mediate biological effects with opposite results. …

2011年3月10日 · CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve …

2024年12月24日 · CXCR3 (C-X-C Motif Chemokine Receptor 3) is a Protein Coding gene. Diseases associated with CXCR3 include Cutaneous Lupus Erythematosus and Pulmonary …

2022年1月18日 · CXCR3 is a chemokine receptor expressed by populations of antigen-experienced CD8+ T cells, including T MEM and T INT cells, and has been implicated in …

2023年7月11日 · Mechanistically, CXCR3 ablation in Treg cells increased tumor antigen-specific cross-presentation by DC1s, increasing CD8 + T cell priming and reactivation in tumors. This …

2023年6月30日 · Here, Moreno Ayala et al. show that CXCR3 expression on Treg cells puts them in close proximity to CXCL9-producing dendritic cells in tumors, where they suppress tumor …

By reviewing the current evidence, we discussed the possible involvement of CXCR3 in neurological diseases. These studies provided hard evidence that CXCR3 plays a vital role in …

Human chemokine receptor CXCR3 (CXCR3-B) transduces apoptotic but not chemotactic signals in microvascular endothelial cells following exposure to high concentrations of CXCL4. CXCR3 …

CXCR3 is a G protein-coupled, seven-transmembrane receptor that binds and is activated by the three IFN-gamma-inducible chemokines of the CXC family named CXCL9, CXCL10, and …