C-X-C chemokine receptor type 6 is a protein that in humans is encoded by the CXCR6 gene. [5] [6] [7] CXCR6 has also recently been designated CD186 (cluster of differentiation 186). …

Oct 11, 2022 · CXCR6 is a receptor for the chemokine CXCL16, which exists as a membrane or soluble form. CXCR6 is a marker for resident memory T (T RM) cells that plays a role in …

Mar 30, 2025 · CXCR6 (C-X-C Motif Chemokine Receptor 6) is a Protein Coding gene. Diseases associated with CXCR6 include Type 1 Diabetes Mellitus 22 and Sarcoidosis 1. Among its …

There are currently six known CXC chemokine receptors in mammals, named CXCR1 through CXCR6. [1][2] CXCR1 and CXCR2 are closely related receptors that recognize CXC …

May 3, 2024 · CXCR6 is a chemokine receptor that exerts its biological effects by binding to its ligand CXCL16. CXCR6 enhances the response of colorectal cancer and melanoma cells to …

CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an …

May 15, 2014 · CXCR6 has been implicated in the localization of cells to the liver due to the constitutive expression of its ligand CXCL16 on liver sinusoidal endothelial cells. Here, we …

Mar 6, 2025 · CXCR6 was identified as a prognostic gene and its expression was predominantly observed in CD8 + T cells. CXCR6 expression positively correlated with improved overall and …

Jul 1, 2008 · Functional CXCR6 expression was up-regulated on developing thymic NKT cells following positive selection but before acquisition of NK1.1 expression. Although CXCR6 was …

Mar 7, 2017 · In contrast to virtually all other chemokine receptors with chemotactic activity, CXCR6 carries a DRF motif instead of the typical DRY motif as a key element in receptor …