CXCR7 is expressed in mature B cells and is involved in the regulation of their development and differentiation , specifically it is highly restricted to marginal zone B cells and its deletion or …

2018年6月21日 · CXCR7, later renamed ACKR3, is a non-classical seven transmembrane-spanning receptor whose function as a signaling or non-signaling scavenger/decoy receptor is …

2023年2月9日 · CXCR7 is frequently upregulated in aggressive cancers, including therapy-resistant neuroendocrine prostate cancer, partially due to the loss of AR and/or HIC1, an …

Although CXCR7 encodes two exons, only the last exon is the solely translated coding region (Broberg et al., 2002). Originally CXCR7 was considered as a receptor for calcitonin gene …

2021年4月15日 · CXCR4/CXCR7 antagonism should prevent the development of metastases by interfering with tumor cell growth, migration and chemotaxis and favoring the frequency of T …

2023年6月26日 · Importantly, the interactions of chemokine members CXCL12 and its receptors CXCR4 and CXCR7 have a broad impact on tumor cell proliferation, survival, angiogenesis, …

CXCR7 is a recently deorphanized receptor for SDF-1 and I-TAC that is highly expressed at the protein level on the surface of malignant cells as compared to cells in normal adult tissues. …

2025年2月27日 · Among the ligand-receptor pairs identified, MIF and its receptor ACKR3 (also known as CXCR7) demonstrated the highest probability (Figure 2A). This route of …

2020年11月23日 · CXCR7 may be neither a simple scavenger nor auxiliary receptor but plays an essential role in cell migration through cooperation with CXCR4. Some chemokine receptors …

2023年6月22日 · CXCR7 is upregulated in neuroendocrine PCa. We have previously reported that CXCR7 is a direct target of AR-mediated transcriptional repression and, as such, it is …