Weighted gene co-expression network analysis reveals that CXCL10, IRF7 …
Furthermore, C-X-C motif chemokine ligand 10 (CXCL10), myxovirus (influenza virus) resistance 1 (MX1), signal transducer and activator of transcription 1 (STAT1), interferon regulatory factor …
Induction of Cxcl10, Ifit1, Irf7 and IFNb1 are more
In addition, both IRF3 and IRF7 can induce IFIT expression independent of classic type I IFN signaling (42). As such, further study of the differences between the upper and lower airway …
Interferon regulatory factor 7 in inflammation, cancer and infection
Interferon regulatory factor 7 (IRF7), a member of the interferon regulatory factors (IRFs) family, is located downstream of the pattern recognition receptors (PRRs)-mediated signaling pathway …
IRF7: activation, regulation, modification and function
2011年4月14日 · Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–Barr virus (EBV) infection, and has since emerged as the crucial regulator...
IRF-7 is the master regulator of type-I interferon-dependent …
2005年4月7日 · Using mice deficient in the Irf7 gene (Irf7-/- mice), we show that the transcription factor IRF-7 is essential for the induction of IFN-alpha/beta genes via the virus-activated, …
汉滩病毒通过TLR3/IRF7/NF-κB途径调控CXCL10的表达 - 百度学术
研究背景:汉滩病毒(hantaan virus,HTNV)是在我国引起肾综合征出血热(hemorrhagic fever with renal syndrome,HFRS)的主要病原体之一.HFRS是一种以发热,出血和急性肾功能损害为特征的 …
IRF7: role and regulation in immunity and autoimmunity
2023年8月9日 · MicroRNAs regulate IRF7 expression by modulating mRNA stability. miR-223 and miR-155-5p enhance IRF7 expression by targeting FOXO3 (37, 38), miR-127 promotes IRF7 …
EMBO丨长期暴露于 TGFb1 以 IRF7 依赖性方式调节骨髓细胞炎症 …
为了证实 IRF7 在 M1 到 M2 转化中的新功能作用，作者使用小干扰 RNA (siRNA) 来沉默 BM-MΦ 离体中的 Irf7 表达（从而将 BM-MΦ 中的 Irf7 水平降低到与 小胶质细胞）并测试了其对促炎 …
CXCL10 - Wikipedia
C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein that in humans is encoded by the …
IRF7: role and regulation in immunity and autoimmunity
2023年8月10日 · In this review, we provide a comprehensive overview on the current knowledge of the role of IRF7 in immunity and autoimmunity. We focus on the latest regulatory …