Calcium/calmodulin-dependent protein kinase kinase 2 is an enzyme that in humans is encoded by the CAMKK2 gene. [5][6] The product of this gene belongs to the serine/threonine-specific …

2024年12月24日 · CAMKK2 (Calcium/Calmodulin Dependent Protein Kinase Kinase 2) is a Protein Coding gene. Diseases associated with CAMKK2 include Parkinson Disease, Late …

Calcium (Ca 2+) is an essential ligand that binds its primary intracellular receptor Calmodulin (CaM) to trigger a variety of downstream processes and pathways.

2021年9月25日 · CAMKK2 deletion suppressed cellular respiration in both cell types, shifting metabolic phenotype to aerobic glycolysis causing the Warburg effect. However, isolated …

该基因的主要亚型通过磷酸化下游激酶 CaMK1 和 CaMK4，在钙/钙调蛋白依赖性 (CaM) 激酶级联中发挥作用。 该基因的蛋白质产物也磷酸化 AMP 活化蛋白激酶 (AMPK) 。 该基因在大脑中 …

Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) is a serine/threonine-protein kinase belonging to the Ca /calmodulin-dependent protein kinase subfamily. CAMKK2 has an …

钙/钙调蛋白依赖性蛋白激酶 II（CaM 激酶 II 或 CaMKII）是一种 丝氨酸 / 苏氨酸 特异性蛋白激酶，由钙/钙调蛋白复合物调节。 CaMKII 参与许多信号传导级联，被认为是学习和记忆的重要中 …

2025年3月8日 · Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling …

2022年10月29日 · Here, we identify calmodulin-dependent kinase kinase 2 (CaMKK2) as a driver of ICB resistance. CaMKK2 is highly expressed in pro-tumor cells and is associated with …

2020年11月2日 · Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) is a serine/threonine-protein kinase belonging to the Ca2+/calmodulin-dependent protein kinase …