Central Areolar Choroidal Dystrophy (CACD) is a rare hereditary dystrophy of the macular area, with fewer than 50,000 persons living with this disorder. It is a well circumscribed, bilateral and symmetrical lesion with loss of retinal and choroidal tissue in the macular area.

Central Areolar Choroidal Dystrophy (CACD) is a genetic disorder causing progressive atrophy of the central choroid and retinal pigment epithelium (RPE), leading to central vision loss. Autofluorescence imaging highlights RPE damage, showing areas of hypo-autofluorescence.

A hereditary macular disorder, usually presenting between the ages of 30-60, characterized by a large area of atrophy in the centre of the macula and the loss or absence of photoreceptors, retinal pigment epithelium and choriocapillaris in this area, resulting in a progressive decrease in visual acuity. Summary.

2024年12月1日 · Central Areolar Choroidal Dystrophy (CACD) is a rare inherited retinal disease characterized by progressive degeneration of the macular area, resulting in central vision loss. CACD typically presents in middle-aged to older individuals, although early signs may appear in younger patients.

In the present study, we analyzed the morphologic findings of 30 genetically confirmed CACD patients and a representative cohort of patients with early- and late-stage nonexudative AMD, to detect discerning features on ophthalmoscopy, FAF, and spectral-domain (SD) optical coherence tomography (OCT).

2008年7月16日 · Central areolar choroidal dystrophy (CACD) is a hereditary retinal disorder that principally affects the macula, often resulting in a well-defined area of atrophy of the retinal pigment epithelium (RPE) and choriocapillaris in the center of the macula. 1–4 Dysfunction of macular photoreceptors usually leads to a decrease in visual acuity ...

CACD is a genetically heterogeneous disorder with mutations in several genes responsible. The majority of patients have one of several mutations in the PRPH2 gene (6p21.1-cen) and the inheritance pattern seems to be autosomal recessive (CACD2).

When caused by a p.Arg142Trp mutation in the peripherin/RDS gene, CACD causes a central cone dystrophy phenotype. This mutation, which most likely originates from a common founder in most patients, is associated with a significant degree of nonpenetrance. In the elderly patient, CACD may be confused …

Central areolar choroidal and retinal pigment epithelial dystrophy (CACD) is a rare hereditary macular disease characterized by a bilateral, symmetric, and well-circumscribed solitary area in the macula with choroidal and retinal pigment epithelial atrophy. We report a family of CACD confirmed by bo …

Central Areolar Choroidal Dystrophy (CACD) is a rare inherited condition that affects the macula, the small area in the middle of the retina that is primarily responsible for our central vision. CACD causes thinning of all of the layers of the retina in the affected area, leading to …