High CAIX expression in the ccRCC group was associated with low ISUP and Furhman grade, low tumor stage and absence of distant metastases. It was also associated with better …

Clinical studies with the CAIX-specific monoclonal antibody (mAb) cG250 have provided unequivocal evidence that ccRCC lesions can be imaged with radiolabeled cG250. Results are …

When intense and diffuse CK7 staining is observed in a clear-cell-predominant tumor, the possibility of CCRCC is less likely. Alternatively, carbonic anhydrase IX (CAIX) was diffusely …

caix 活性 (caix off) 和 nfs1 表达的组合抑制导致细胞内酸中毒和铁硫簇的失调，从而导致 ros 增加、脂质过氧化的诱导和铁死亡的促进。 缺氧诱导的CAIX活性和铁死亡介导的癌细胞死亡

2024年6月3日 · Carbonic anhydrase IX (CAIX), a zinc metal transmembrane protein, is highly expressed in 95% of clear cell renal cell carcinomas (ccRCCs). A positron emission …

2022年3月9日 · The carbonic anhydrase isoform IX (CAIX) enzyme is constitutively overexpressed in the vast majority of clear cell renal cell carcinoma (ccRCC) and can also be …

ELISA provides a quantitative and objective method to measure CAIX levels in renal tumors. The tissue CAIX levels measured with ELISA highly correlate with the results obtained with the …

2010年7月1日 · CAIX expression on primary ccRCC tumours is a prognostic factor for survival and is a predictor of response to IL-2 immunotherapy in ccRCC patients. Whether high CAIX …

2013年5月9日 · In this issue of the BJUI, Zhang et al. 1 publish the results of a study on the prognostic role of carbonic anhydrase IX (CAIX), an antigen almost invariably present in clear …

2024年12月23日 · 本文探索了靶向放射性核素治疗 (TRT)与免疫检查点抑制剂 (ICI)联合治疗晚期透明细胞肾细胞癌 (ccRCC)的新策略，通过使用特异性靶向肿瘤抗原CAIX的 [177Lu]Lu-DOTA …