
Pathology Outlines - CD3
Mar 18, 2022 · CD3 gamma, delta and epsilon defects cause autosomal recessive severe combined immunodeficiency (no T cells, although B cells and NK cells are normal) (Pediatr …
Pathology Outlines - CD20
Sep 20, 2021 · 33kd phosphoprotein with 3 hydrophobic regions that traverse the cell membrane, creating a structure similar to an ion channel that allows for the influx of calcium required for …
Pathology Outlines - CD30-39
May 6, 2021 · Member of tetraspanin family (members have 4 hydrophobic domains, others are CD9, CD53, CD63, CD81, CD82 and CD151)
Pathology Outlines - CD45 (LCA)
2 days ago · Lymph node, right cervical excision: Nodular lymphocyte predominant Hodgkin lymphoma (see comment) Comment: There is total replacement of the nodal architecture by …
Pathology Outlines - CD123
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), with marked enhancement in specificity when used alongside TCF4, CD4, CD56, TCL1 and CD303, though CD303 can be negative in …
Pathology Outlines - Reactive lymphadenopathy
Dec 4, 2024 · Answer A is incorrect because Burkitt lymphoma is a diffuse proliferation of medium sized atypical lymphoid cells with blastoid morphology and conspicuous 1 - 3 nucleoli. Answer …
Stains & CD markers - Pathology Outlines - CD10
Jan 17, 2023 · CD10- is associated with t(v;11q23.3); KMT2A (MLL) rearrangement, infantile (< 1 year of age) presentation and poor prognosis (Leukemia 2002;16:1233) May distinguish B …
Pathology Outlines - CD15
Mar 19, 2024 · Also known as LeuM1, Lewis X, 3-fucosyl-N-acetyl-lactosamine Mediates phagocytosis and chemotaxis Synthesis is directed by FUT4 (OMIM #104230) in lymphoid …
Pathology Outlines - BCL6
Aug 3, 2023 · Coexpression of BCL6 and BCL2 by immunohistochemistry is abnormal and can help distinguish follicular lymphoma (85 - 90% in grade 1 - 2, < 50% in grade 3) from reactive …
Pathology Outlines - CD63
2 days ago · CD Markers - CD63. Also called NKI-C3 (J Natl Cancer Inst 1992;84:422), lysosomal membrane-associated glycoprotein 3, LAMP-3, melanoma associated antigen and ME491