Cadherin-5, or VE-cadherin (vascular endothelial cadherin), also known as CD144 (Cluster of Differentiation 144), is a type of cadherin. It is encoded by the human gene CDH5. [5]

Vascular-endothelial cadherin (CD144)- but not PECAM-1 (CD31)-based cell-to-cell contacts convey the maintenance of a quiescent endothelial monolayer

Anti-VEGFR2 and CD144 are endothelial cell markers, as they bind to the VEGF and VE-Cadherin receptors, respectively. In addition, by differentiating between mature and precursor endothelial cells, CD133 helped the identification of CECs as a stem cell marker.

2005年8月1日 · After the onset of definitive hematopoiesis, CD144 (vascular endothelial [VE]–cadherin) has been considered a specific marker of endothelial cells. In contrast, we found that virtually all HSC activity from embryonic day 13.5 (E13.5) fetal liver was CD144 +.

Forty one genes (Section VI) are upregulated at the angioblast stage (day 3.5, CD144-positive), during later stages of endothelial differentiation in the embryoid body (day 6.5, CD144-positive) and in CD144-positive cells of the embryo at day 9.5.

CD144 has been shown to promote tumour angiogenesis, invasion and metastasis in malignant tumours. The purpose of the present study was to investigate the clinical prognostic significance of CD144 in advanced gastric cancer (GC) to complement the American Joint Committee on Cancer (AJCC) 8th Edition …

2020年10月1日 · 在晚期 GC 患者中，CD144 的表达水平是评估疾病预后风险的有用预后指标。表明CD144的表达是DFS的独立预测因子，Borrmann型和CD144的表达是OS的独立预测因子（p<0.05）。列线图通过结合 Borrmann 类型和 CD144 的表达水平来评估 III 期 GC 的风险。

After the onset of definitive hematopoiesis, CD144 (vascular endothelial [VE]–cadherin) has been considered a specific marker of endothelial cells. In contrast, we found that virtually all HSC activity from embryonic day 13.5 (E13.5) fetal liver was CD144 +.

2005年8月1日 · After the onset of definitive hematopoiesis, CD144 (vascular endothelial [VE]-cadherin) has been considered a specific marker of endothelial cells. In contrast, we found that virtually all HSC activity from embryonic day 13.5 (E13.5) fetal liver was CD144+.

Here, we evaluated the feasibility of quantifying mRNA levels of the endothelium-associated markers CD31, CD144, CD146 and von Willebrand factor (vWf) in peripheral blood (PB) of healthy donors, patients, and human umbilical veins by real-time reverse transcriptase polymerase chain reaction (RT-PCR) and their use as surrogate markers for CEC.