CTLA-4 - 百度百科
细胞毒T淋巴细胞相关 抗原 4（cytotoxic T lymphocyte-associated antigen-4, CTLA-4）又名CD152，是一种 白细胞分化抗原 ，是T细胞上的一种跨膜受体，与CD28共同享有B7分子配 …
Cytotoxic T-lymphocyte associated protein 4 - Wikipedia
Cytotoxic T-lymphocyte associated protein 4, (CTLA-4) also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and …
肿瘤免疫靶点 | CTLA-4 - 知乎 - 知乎专栏
ATOR-1015是抗OX40/CTLA-4双特异性抗体，与调节性T细胞（抑制免疫系统的细胞）上的CTLA-4和OX40结合，激活巨噬细胞以杀死Treg，消除Treg对有益T细胞的抑制作用，同时效应T细 …
CTLA-4的结构与功能：免疫抑制药物研发的基石 - 知乎
细胞毒T淋巴细胞相关抗原4（cytotoxic T lymphocyte-associated antigen-4, CTLA-4）又名CD152，是一种白细胞分化抗原，是T细胞上的一种跨膜受体，与CD28共同享有 B7分子配体 …
CTLA-4 - 维基百科，自由的百科全书
CTLA4 又稱 CTLA-4 （細胞毒性T淋巴細胞相關抗原4，cytotoxic T-lymphocyte-associated protein 4）或 CD152 （分化群 152），是一种 蛋白质受体 [7]。 CTLA-4蛋白由小鼠的Ctla4 [8] 和人 …
Current Understanding of Cytotoxic T Lymphocyte Antigen-4 …
Cytotoxic T lymphocyte antigen-4 (CTLA-4, CD152) is a 25 kDa molecule composed of a leader peptide, a ligand binding domain, a transmembrane domain, and a cytoplasmic domain. Three …
CTLA4 Gene - GeneCards | CTLA4 Protein | CTLA4 Antibody
2024年12月24日 · CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4) is a Protein Coding gene. Diseases associated with CTLA4 include Immune Dysregulation With Autoimmunity, …
CTLA-4 (CD152): A versatile receptor for immune-based therapy
CD152 (CTLA-4) determines the unequal resistance of Th1 and Th2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function
CTLA-4 (CD152): A versatile receptor for immune-based therapy
Coreceptor-based immunotherapy is a rapidly developing approach to treat cancer patients. Among those targeted receptors, CTLA-4 is the primary attenuator of adaptive immune …
Differential expression of CTLA-4 among T cell subsets - PMC
CTLA-4 (CD152), the CD28 homologue, is a costimulatory molecule with negative effects on T cell activation. In addition to its role in the termination of activation, CTLA-4 has been …