NKG2 also known as CD159 (C luster of D ifferentiation 159) is a receptor for natural killer cells (NK cells). There are 7 NKG2 types: A, B, C, D, E, F and H. NKG2D is an activating receptor on the NK cell surface. NKG2A dimerizes with CD94 to make an inhibitory receptor (CD94/NKG2). IPH2201 is a monoclonal antibody targeted at NKG2A. [1]

2021年12月20日 · 研究发现COVID-19患者体内的CD8+T和NK细胞的数量较健康人显著降低, 但两种细胞表面的NKG2A表达均升高，而康复后机体内的NK和CD8+T细胞的数量升高至正常值, …

Clone REA110 recognizes CD159a, an inhibitory natural killer (NK) cell receptor. CD159a forms heterodimer with CD94 and contains a C-type lectin ectodomain.

NKG2A (CD159a) forms a disulfide-bonded heterodimer with CD94 that can bind to MHC class I HLA-E molecules on target cells and inhibit NK cell activation.</span>

CD159a, also known as NKG2A or KLRC1, is a type II transmembrane protein. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and T cell subsets. NKG2A is an inhibitory NK cell receptor and it is expressed as a heterodimer with

Clone REAL283 is an antibody fragment derived from the full CD159a (NKG2A) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. Clone REAL283 recognizes CD159a, an inhibitory natural killer (NK) cell receptor.

CD159a, also known as NKG2A or KLRC1 (killer cell lectin-like receptor subfamily C, member 1), is a 43 kD type II transmembrane protein with extracellular C-type lectin domains. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and activated CD8+ T cells.

CD159a (NKG2AB6) is an ~40 kDa single-pass type II transmembrane glycoprotein that is encoded by Klrc1 (Killer cell lectin-like receptor subfamily C member 1). This NKG2 receptor is comprised of an extracellular region with one C-type lectin domain followed by a transmembrane segment and a cytoplasmic tail with two immunoreceptor tyrosine-based ...

CD159a (NKG2a) is a 40 kDa (reduced), 75 kDa (unreduced) type II transmembrane protein associated with CD94 to form a disulphide-linked heterodimer. CD159a is a member of the Ca 2+ -dependent (C‑type) lectin family.