
Human leukocyte antigen - Wikipedia
The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The …
人類白細胞抗原 - 维基百科,自由的百科全书
人類白細胞抗原(英語: Human leukocyte antigen ,缩写: HLA ),是編碼人类的主要组织相容性复合体(MHC)的基因。 其位于 6号染色体 的短臂上(6p21.31),包括一系列紧密连锁 …
免疫系统之 HLA 与MHC - 知乎 - 知乎专栏
人类白细胞抗原 (英语:human leukocyte antigen)- HLA是在6号染色体短臂上的一类基因,编码 MHC蛋白质 。HLA有不同的基因座,编码两大类MHC蛋白。 HLA高度多态性,同一种基 …
The HLA System: Genetics, Immunology, Clinical Testing, and …
Initial efforts to expand cord blood progenitors ex vivo have resulted in expansion of mature rather than immature hematopoietic stem cells. The HLA system is the major histocompatibility …
Human Leukocyte Antigen (HLA) System: Genetics and …
The cell-mediated adaptive immune response is regulated by the major histocompatibility complex (MHC) or human leukocyte antigen (HLA) in humans . HLA molecules are cell surface …
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution: Cell
2017年11月30日 · Using LOHHLA, we find that HLA LOH occurs in 40% of non-small-cell lung cancers (NSCLCs) and is associated with a high subclonal neoantigen burden, APOBEC …
Neutrophil profiling illuminates anti-tumor antigen ... - Cell Press
2024年3月5日 · We observed increased T cell proliferation with HLA-DR + neutrophils; further work is needed to detail how they directly activate T cells. Testing antigen presentation to T …
Biochemistry, HLA Antigens - StatPearls - NCBI Bookshelf
2023年4月24日 · Human leukocyte antigens (HLA) are genes in major histocompatibility complexes (MHC) that help code for proteins that differentiate between self and non-self. They …
Major histocompatibility complex: Antigen processing and …
2013年7月18日 · The main function of HLA class I gene products (HLA-A, -B, and -C) is to present endogenous peptides to responding CD8+ T Cells while the class II coded molecules …
An archaic HLA class I receptor allele diversifies natural killer cell ...
2024年10月29日 · Polymorphic human leukocyte antigen (HLA) class I and killer cell immunoglobulin-like receptors (KIRs) are key regulators of natural killer (NK) cells, which …