
cGAS antibody (26416-1-AP) | Proteintech - ptglab
26416-1-AP targets cGAS in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for …
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cGAS (E5V3W) Rabbit mAb #79978 - Cell Signaling Technology …
Monoclonal Antibody for studying cGAS. Validated for F, IF, IHC, WB, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, cGAS (E5V3W) Rabbit Monoclonal Antibody (CST #79978) is ready to ship.
【研究专题】免疫信号通路cGAS-STING - 知乎 - 知乎专栏
cgas-sting通路是细胞内重要的免疫信号通路,负责识别病毒和细菌的双链dna(dsdna)。 cGAS结合dsDNA后生成环状GMP-AMP(cGAMP),激活STING(刺激性基因)。 活化的STING进一步招募TBK1并激活IRF3,促进I型干扰素和…
cGAS Antibody (D-9) | SCBT - Santa Cruz Biotechnology
cGAS Antibody (D-9) is a mouse monoclonal IgG2a kappa light chain antibody that detects cGAS of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-cGAS antibody (D-9) is available in both non-conjugated and various conjugated forms ...
cGAS 抗体 | SCBT - Santa Cruz Biotechnology
环gmp-amp合酶(cgas)是一种检测细胞膜dna的关键酶,它通过产生环gmp-amp(cgamp)启动免疫反应,从而激活sting通路。 cGAS-STING 通路在先天性免疫反应中发挥着重要作用,影响着炎症和自身免疫性疾病的发展。
PNAS | 中国科大高大兴、项晟祺课题组揭示cGAS动态相分离调控 …
该研究主要探讨了 cgas 蛋白的相变和酶活性的调控机制,通过综合运用生化、核磁共振( nmr )波谱学和细胞生物学等手段,我们揭示了 cgas 的 n 端无序区( idr ),如何精细调控 cgas 的相变凝聚相的材料特性。
尹航课题组揭示棕榈酰化修饰调控天然免疫“哨兵”cGAS抵抗病毒感 …
cgas可识别病原体双链dna分子,是启动抗病毒天然免疫防御的重要“哨兵”之一。 除了抗病毒感染,cGAS介导天然免疫信号通路还在肿瘤免疫和自身炎症等疾病发生中发挥重要功能。
抑制TRABID可通过有丝分裂和自噬失调激活cGAS、STING介导的 …
研究结论:因此,研究人员的研究描述了TRABID缺乏在阻止cGAS自噬降解中的作用。 ... 肿瘤切片的免疫组化(IHC)分析表明,Trabid缺失细胞的肿瘤表现出增殖减少和凋亡增加,Ki67和活性caspase-3染色分别证明了这一点。
cGAS Antibody - BSA Free - Novus Biologicals
View Rabbit Polyclonal anti-cGAS Antibody - BSA Free (NBP1-86761). Validated Applications: WB, Simple Western, ICC/IF, IHC. Validated Species: Human. Validated by: Orthogonal Strategies. Sample size available.
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cGAS antibody (29958-1-AP) | Proteintech - ptglab
29958-1-AP targets cGAS in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at …