cGAS (D1D3G) Rabbit mAb #15102 - Cell Signaling Technology …
Monoclonal Antibody for studying cGAS. Validated for WB, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, cGAS (D1D3G) Rabbit Monoclonal Antibody (CST #15102) is ready to ship.
cGAS antibody (29958-1-AP) | Proteintech | 武汉三鹰生物技术有限 …
29958-1-AP targets cGAS in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Anti-cGAS抗体(ab224144) - Abcam中文官网
WB Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 59 kDa. Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP.
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cGAS antibody (26416-1-AP) | Proteintech - ptglab
Detects authentic cGAS band ~58kDa by western blot that disappears upon knockdown, but also detects a non-specific band just above, ~60kDa, which is not ideal for figure generation and concerning for other applications such as IF.
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【研究专题】免疫信号通路cGAS-STING - 知乎 - 知乎专栏
cgas-sting通路是细胞内重要的免疫信号通路，负责识别病毒和细菌的双链dna（dsdna）。 cGAS结合dsDNA后生成环状GMP-AMP（cGAMP），激活STING（刺激性基因）。 活化的STING进一步招募TBK1并激活IRF3，促进I型干扰素和…
Anti-cGAS Antibodies | Invitrogen - 赛默飞世尔科技公司
Antibodies that detect cGAS can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. These antibodies target cGAS in Human, Mouse, Rat and Porcine samples. Our cGAS polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse.
Mitochondrial DNA release via the mitochondrial permeability …
2024年6月13日 · The activation of the cGAS-STING pathway, triggered by mitochondrial DNA (mtDNA) release, has been implicated in the onset of KD. However, its specific role in the progression of inflammation during KD's acute phase remains unclear. We measured mtDNA and 2’3’-cGAMP expression in KD patient serum using RT-qPCR and ELISA.
cGAS Recombinant Rabbit Monoclonal Antibody (10H1L5) - 赛默 …
Invitrogen Anti-cGAS Recombinant Monoclonal (10H1L5), Catalog # 703149. Tested in Western Blot (WB) applications. This antibody reacts with Mouse samples. Supplied as 100 µg purified antibody (0.5 mg/mL).
探究cGAS-STING信号通路-MedSci.cn - 梅斯医学MedSci
2025年2月11日 · 当前，全球已有数十款靶向cgas或sting的药物进入临床试验，用于治疗实体瘤、自身免疫性疾病和慢性病毒感染。因此，系统解析cgas-sting通路的生物学奥秘将为人类疾病的药物研发提供重要靶点，为相关疾病的治疗带来新策略和新希望。-01-cgas-sting信号通路的发现
Western blot analysis of lysates from wild type (WT) and cGAS knockdown (KD) HeLa cells using [KD Validated] cGAS Rabbit PolymAb® (A8335PM) at 1:12000 dilution incubated at room temperature for 1.5 hours. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 30 μg per lane.