Central giant-cell granuloma (CGCG) is a localised benign condition of the jaws. It is twice as common in females and is more likely to occur before age 30. Central giant-cell granulomas are more common in the anterior mandible, often crossing the midline and causing painless swellings. [1]

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The central giant cell granuloma (CGCG) was once thought to represent reactive lesion, however the unpredictable and sometimes occasionally aggressive behavior and because of its possible relationship to tumors of long bone and some syndromes, it is best classified as benign neoplasm.

Central giant cell granuloma (CGCG) is an uncommon, benign but aggressive osteolytic neoplasm of the craniomaxillofacial region, histologically characterized by an abundance of evenly distributed multinucleated giant cells within a sea of ...

CGCG is a benign, non-neoplastic proliferative intraosseous lesion of the jaw with an unknown etiology, which is diagnosed during the first two decades of life. CBCT offers more information about lesion extension and cortical wall integrity and aids in diagnosis.

Central giant cell granuloma (CGCG) of the jaws is a benign, intraosseous, osteolytic lesion of debatable etiology. CGCG lacks in clinical and radiographical pathognomonic features to distinguish from common lesions occurring in this region.

Central Giant Cell Granuloma (CGCG) is a benign yet potentially aggressive lesion found predominantly in the mandible, although it can also appear in other craniofacial bones. Despite its benign nature, CGCG demands careful attention due to its capacity for bone resorption and the recurrence rate post-treatment.