Concentrated growth factor (CGF) is an emerging trend in periodontology and now in implant dentistry. Various studies have been published in the literature evaluating the effect of CGF on implant osseointegration, implant stability, survival rate, sinus augmentation, and peri-implant defects. However, no systematic review has yet been documented.

2024年4月12日 · Recently, one clinical study evaluated the combined use of concentrated growth factors (CGFs) and adipose-derived stem cells (ADSCs) as cytokines and seed cells for bone regeneration in patients...

CGF contains GFs such as VEGF, PDGF, IGF-I and TGF-β1. Compared to PRF, CGF contains a denser and richer GF‒fibrin matrix. Furthermore, CGF has a 3D fibrin network in which growth factors are closely bound to one another. This provides the slow release of growth factors, which helps with wound healing [18,27]. 1.7. The Technique

2018年9月4日 · CGF is a fibrin tissue adhesive with haemostatic and tissue sealing properties. It promotes wound healing and accelerates osteogenesis. CGF improves the stability of the wound that is required for the attachment of a new connective tissue to the root surface. It promotes epithelial, endothelial and epidermal regeneration and decreases scarring.

2024年12月5日 · Micro-CT analyses indicated better bone mineral density and microarchitecture in the CGF group. One year after implant restoration, both groups showed 100% success rates. CGF application may effectively reduce bone resorption and promote new bone regeneration postextraction [8, 157, 158].

CGF is a fibrin tissue adhesive with haemostatic and tissue sealing properties. It promotes wound healing and accelerates osteogenesis. CGF improves the stability of the wound that is required for the attachment of a new connective tissue to the root surface. It promotes epithelial, endothelial and epidermal regeneration and decreases scarring.

2021年6月19日 · The use of CGF for DPC regeneration in clinical practice has yielded promising results. CGF is mainly used as root canal filling material to regenerate pulp tissue and pulp capping material to seal the pulp cavity.

2018年9月11日 · CGF is a fibrin-rich organic matrix obtained by centrifuging of the patient's venous blood, and is considered a third generation platelet enrichment that does not require any additional reagents...

Purpose: To assess the impact of autologous concentrated growth factors (CGF) on alveolar ridge absorption and osteogenesis following posterior tooth extraction. Materials and methods: Fifty patients were randomly assigned to have extraction sockets treated with CGF or no treatment.

2020年8月15日 · This article elucidates the utilization of a novel platelet concentrate-concentrated growth factor (CGF) for rapid and successful healing outcome in regenerative endodontics. This case report focusses on two cases: 23-year-old and 21-year-old patients with incomplete root formation and periapical le …