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2018年7月30日 · A single copy of each FMR-(CGG) n-HyTK cassette containing 0, 53, or 153 (CGG) n repeats was inserted into the RL5 site in MEL cells via Cre–loxP-mediated exchange with a pre-existing eGFP ...

2010年2月17日 · Purpose: Fragile X syndrome is caused by expansion and subsequent methylation of a CGG trinucleotide repeat in the FMR1 5′-untranslated region. Southern blot analysis is typically required to ...

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2020年10月8日 · Two CGGG/CGGG sites are simultaneously recognized by two p-NCTB molecules resulting in the formation of interhelical (inter- and intrastrand) binding complexes (Fig. 1 c and d, ... (G 4 C 2) n with different repeat number. Since G 4 C 2 repeat become pathogenic only when the repeat number exceeds the threshhold, binding to the expanded d ...

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2024年12月10日 · 所以cmg和cgg是..他说我吧龄十年难道没听过，那还真是活了20多年没见过这么奇怪的中文