慢性移植物抗宿主病（cGVHD）指异基因造血干细胞移植（allo-HSCT）后，受者在重建供者免疫的过程中，来源于供者的淋巴细胞攻击受者脏器产生的临床病理综合征（包括经典型cGVHD …

2017年12月28日 · We discuss these therapeutic strategies in the context of the pathophysiology of chronic GVHD, emphasizing the central roles of B-cell signaling, naive T-cell differentiation …

慢性移植物抗宿主病（chronic graft-versus-host disease，cGVHD）是异基因造血干细胞移植后常见的并发症之一，可累及多个器官，发生率为30%~70% [1-2]。 其中，眼部cGVHD的发生率 …

慢性移植物抗宿主病(cGVHD)指异基因造血干细胞移植(allo-HSCT)后 ,受者在重建供者免疫的过程中,来源于供者的淋巴细胞攻击受者脏器产生的临床病理综合征(包括经典型cGVHD和重叠综合 …

Chronic graft versus host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. Clinically, chronic GVHD is a pleiotropic, …

2024年4月11日 · Chronic GVHD (cGVHD) is the most relevant cause of late non-relapse morbidity and subsequent mortality (approximately 25%) following allo-HCT (Grube et al. 2016).

2000年12月15日 · To accelerate development and approval of novel therapeutic agents in chronic GVHD, quantitative research tools are needed to measure short-term responses to treatment …

2022年11月25日 · Chronic graft-vs-host disease (cGVHD) is a common complication and a major cause of morbidity and mortality following allogeneic hematopoietic cell transplantation. It is …

2024年9月25日 · Graft-versus-host disease (GVHD) can develop after allogeneic hematopoietic cell transplant (HCT) when immune cells from a non-identical donor (the graft) initiate an …

Chronic graft-versus-host disease (cGVHD) is a complication of hematopoietic cell transplantation (HCT). Although the clinical outcomes of cGVHD are well documented, few studies have …