Mechanisms for induction of mutations and chromosome …
Genotoxic agents induce chromosomal alterations, such as aberrations, micronuclei, and sister chromatid exchanges as well as mutations both in vivo and in vitro. Ionizing radiation and …
Chromosome Fusion Affects Genetic Diversity and Evolutionary …
Our findings show that the ten smallest chromosomes in Dryas and Euiedes, which are fused in Heliconius, have a distinct genomic and gene-structural composition. Chromosome fusions are …
Chromosomes and Chromatin - The Cell - NCBI Bookshelf
The sequences at the ends of eukaryotic chromosomes, called telomeres, play critical roles in chromosome replication and maintenance. Telomeres were initially recognized as distinct …
Structural Chromosome Instability: Types, Origins, …
Chromosome instability (CIN) is characterized by an increased accumulation of numerical and structural changes in chromosomes and is a common feature of solid tumors and some …
A map of parental-DNA exchanges charts course for studies of …
1 天前 · Human genetic diversity and evolution rely on new mutations and exchange of DNA between chromosomes during the generation of sex cells, in a process called recombination. …
Chromosomal Mutations - SpringerLink
2023年9月27日 · The mutations can be grouped into two broad categories: genetic mutations (or changes that affect the nucleotide structure of a gene), and chromosomal mutations, in which …
A de novo, mosaic and complex chromosome 21 rearrangement …
19 小时之前 · Copy number variation (CNV) of the amyloid-β precursor protein gene (APP) is a known cause of autosomal dominant Alzheimer disease (ADAD), but de novo genetic variants …
A dual role of Cohesin in DNA DSB repair - Nature
3 天之前 · Initially described as a driver of sister chromatid cohesion 7,8, cohesin also regulates the topology of chromosomes by extruding chromatin through its ringlike structure to form DNA …
Overview of Chromosomal Mutations, Types & Examples
2023年12月11日 · Chromosomal mutations are any alterations or errors that occur on a chromosome. In living organisms, mutations occur at one in every ten million cell replications. …
Types of Chromosome Mutations - SpringerLink
2023年2月28日 · Structural chromosome aberrations or chromosome mutations represent apart from aneuploidies the most frequent pathologic findings in applied chromosome diagnostics. …