Chunbin Zou, MD, PhD. Pulmonary, Allergy and Critical Care Medicine. Associate Professor of Medicine. Email: [email protected]. Phone: 412-624-3666

LPS impairs phospholipid synthesis by triggering β-transducin repeat-containing protein (β-TrCP)-mediated polyubiquitination and degradation of the surfactant enzyme acyl-CoA … C Zou, PL Butler,...

Dr. Zou’s laboratory focuses on a novel epigenetic code histone O -palmitoylation and its pathophysiological significances. Zou serendipitously discovered a novel histone modification called histone O -palmitoylation that acts as a new epigenetic mark to regulate gene transcription.

Chunbin ZOU, Associate Professor | Cited by 1,627 | of University of Pittsburgh, PA (Pitt) | Read 79 publications | Contact Chunbin ZOU

2021年9月3日 · In this study, we report that a chromatin modulator protein arginine N-methyltransferase 4/coactivator-associated arginine methyltransferase 1 (PRMT4/CARM1) is elevated in human lung tissues with pneumonia and in experimental lung injury models.

Chunbin Zou, MD, PhD. Dr. Zou’s laboratory focuses on the molecular behavior of a group of chromatin modulators in lung injury. Microbial pathogens may take advantage of and hijack these molecules or pathways to cause lung epithelial cell death or reprogram innate and adaptive immunity, thus worsening or accelerating the progression of lung ...

Critical resources supporting researchers and trainees include extensive biorepositories and patient cohorts, local and national databases, and statistical expertise, as well as access to innovative technical approaches including cutting-edge human tissue-based disease modeling, high-throughput systems for drug discovery and validation, and syst...

Dr. Zou's lab focuses on the studies of protein stability and availability of epigenetic enzymes or chromatin modulators in disease models of lung injury and acute respiratory distress syndrome.

ORCID record for Chunbin Zou. ORCID provides an identifier for individuals to use with their name as they engage in research, scholarship, and innovation activities.

Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA 15213, USA.