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CD44, the best characterized of all HA receptors, is a ubiquitous family of non-kinase, type 1 cellular hyaladherins with many described functions. CD44 mediates cell motility, inflammation, lymphocyte homing, and cell growth including tumorigenesis, but also participates in HA clearance and injury resolution.

Interleukin 4 (IL-4) is a pleiotropic type I cytokine that controls both growth and differentiation among haemopoietic and non-haemopoietic cells. Its receptor is a heterodimer. One chain, the IL-4R alpha chain, binds IL-4 with high affinity and determines the nature of the biochemical signals that are induced.

A cell-associated hyaluronan-binding protein (cell-HABP) has been isolated from locomoting fibroblasts that may represent one binding site that transduces these effects of hyaluronan. This protein is concentrated in the lamellae and ruffles of migrating fibroblasts but is lost from the cell surface as cell locomotion slows.

Ciba Health is a digital health solution that blends root-cause medicine, physician-led care teams, and AI to prevent and reverse chronic diseases. Root-cause medicine focuses on treating the underlying cause of illness, rather than providing temporary fixes…

2015年1月9日 · Natural killer (NK) cells recognize and eliminate transformed or infected cells that have downregulated MHC class-I and express specific activating ligands. Recent evidence indicates that allogeneic NK cells are useful to eliminate haematological cancer cells independently of MHC-I expression.

CIBA是新加坡第一个被国际原子能机构选中和认可的合作中心，加入了一批在世界核科学和技术方面做出杰出贡献的高标准技术中心。 Additionally, CIBA is leading an IAEA Coordinated Research Project (CRP) on single-cell imaging and irradiation using accelerator-based techniques for applications in radiobiology and cancer treatment.

1992年6月6日 · Antibodies to peptides encoded in the cDNA react in immunoblot assays with the 58- and 52-kD proteins of a novel hyaluronan receptor complex previously implicated in cell locomotion. Furthermore, antibodies specific to the 58- and 52-kD proteins, which block ras-induced locomotion, also cross-react with the expressed, encoded protein.

2019年10月1日 · The new beam-line facility dedicated to the study of the radiobiology of single cells was constructed at the Centre for Ion Beam Applications (CIBA) in response to an increase in demand in Singapore for studies into the cell response to controlled doses of protons.

Microbial Cell Walls. CIBA Lectures in Microbial Biochemistry. M. R. J. Salton . Philip E. Hartman