circMbl functions in cis and in trans to regulate gene expression …
Muscleblind (mbl) is an essential muscle and neuronal splicing regulator. Mbl hosts multiple circular RNAs (circRNAs), including circMbl, which is conserved from flies to humans. Here, …
circRNA biogenesis competes with pre-mRNA splicing - PubMed
2014年10月2日 · Modulation of MBL levels strongly affects circMbl biosynthesis, and this effect is dependent on the MBL binding sites. Together, our data suggest that circRNAs can function in …
circMbl functions in cis and in trans to regulate gene expression …
2022年4月26日 · Muscleblind (mbl) is an essential muscle and neuronal splicing regulator. Mbl hosts multiple circular RNAs (circRNAs), including circMbl, which is conserved from flies to …
The biogenesis, biology and characterization of circular RNAs
2019年8月8日 · One of the first examples of a circRNA functioning as a protein sponge came from a study of the splicing factor protein gene that encodes muscleblind (mbl) in D. melanogaster; …
circRNA Biogenesis Competes with Pre-mRNA Splicing - Cell …
2014年10月2日 · Modulation of MBL levels strongly affects circMbl biosynthesis, and this effect is dependent on the MBL binding sites. Together, our data suggest that circRNAs can function in …
重磅综述：环状RNA的调控机制和细胞功能 - circRNA论坛
如在黑腹果蝇中，RBP Muscleblind （Mbl）通过与侧翼内含子中的Mbl结合位点结合，促进了circRNA circMbl的产生。 与单个基因的观察不同，QKI与人类细胞上皮-间质转化过程中数百 …
Muscleblind (mbl) is an essential post-transcriptional regulator involved in muscle and photoreceptor development (Begemann et al., 1997; Vicente-Crespo et al., 2008). MBL …
Circular RNA: an important player with multiple facets to …
2021年3月5日 · Circular RNAs (circRNAs), a novel type of endogenous RNAs with covalently closed-loop structures, have become a new research hotspot in the RNA world. Their …
circMbl functions in cis and in trans to regulate gene expression …
Muscleblind (mbl) is an essential muscle and neuronal splicing regulator. Mbl hosts multiple circular RNAs (circRNAs), including circMbl, which is conserved from flies to humans. Here, …
Cell | 环形RNA潜力如何？非编码RNA领域大牛陈玲玲解答 - 知乎
第一个作为蛋白海绵被发现的circular RNA是circMbl，它与MBL (multifunctional protein muscleblind) 之间存在反馈环调控。 MBL通过结合在circMbl 内含子的侧端，促进circMbl的生物 …