Climbing fibers are the name given to a series of neuronal projections from the inferior olivary nucleus located in the medulla oblongata. [1] [2] These axons pass through the pons and …

In most models of cerebellum function, the climbing fibers regulate movement by modulating the effectiveness of the mossy—parallel fiber connection with the Purkinje cells. The Purkinje cells …

Climbing fibers are a unique structure of the cerebellum with no homologs elsewhere in the central nervous system. They originate from the inferior olive in the medulla oblongata. Each …

Climbing fibers are a unique structure of the cerebellum with no homologs elsewhere in the central nervous system. They originate from the inferior olive in the medulla oblongata.

2023年7月27日 · Climbing fibers. These fibers arise from the inferior olivary nucleus and send collaterals to the deep nuclei before entering the cerebellar cortex. These fibers will reach …

Climbing fibers are the terminals of the axons arriving from inferior olive neurons that form strong synaptic connections to Purkinje cells. From: Fundamental Neuroscience (Fourth Edition), 2013

Climbing fiber (CF) inputs to the cerebellar cortex represent one of the strongest candidates in the vertebrate brain for conveying neural instructive signals.

2024年4月2日 · Climbing fiber (CF) inputs to the cerebellar cortex represent one of the strongest candidates in the vertebrate brain for conveying neural instructive signals.

2019年3月27日 · One significant input to the Purkinje cells, are long-range projections called climbing fibers. “Climbing fibers are very well-known and extensively studied in the field.” …

Climbing fibre field potentials evoked by stimulation of cutaneous superficial radial nerve afferents were used as a measure of the excitability. At most recording sites climbing fibres had their …

Climbing fibers originate from only one precerebellar nucleus, the contralateral inferior olive. Each Purkinje cell is directly innervated by a single climbing fiber. One is enough. A climbing fiber …

2020年9月7日 · Climbing fibers from the inferior olive make strong excitatory synapses onto cerebellar Purkinje cell (PC) dendrites and trigger distinctive responses known as complex …

2024年6月12日 · In classical cerebellar learning, Purkinje cells (PkCs) associate climbing fiber (CF) error signals with predictive granule cells (GrCs) that were active just prior (∼150 ms). …

Climbing fibers are "lazy" (but strong), thus Purkinje cells exhibit complex spikes at a rate of about 1 per second. The illustration above depicts an intracellular recording from a Purkinje cell that …

Here, we argue that climbing fiber signaling is about adjusting relative probabilities for the induction of LTD and long-term potentiation (LTP) at parallel fiber synapses. Complex spike …

2018年9月17日 · Cerebellar climbing fibers provide predictive, context-specific instructional signals that do not rely exclusively on motor errors to support learning of arbitrary …

2016年1月25日 · Our results show that stimulating climbing fibers at 0.5–3 Hz induces a frequency-dependent, graded suppression of Purkinje cell activity. Climbing fiber stimulation at …

2023年7月27日 · Images of thousands of Purkinje cells show that nearly all human cells have multiple primary dendrites, a structure that, when observed in mice, allows connections with …

2006年11月15日 · These findings, in combination with analyses of the distribution of labeled neurons in two major brainstem sources of mossy fibers, suggest that the mossy fiber system …

2009年7月6日 · Here, we argue that climbing fiber signaling is about adjusting relative probabilities for the induction of LTD and long-term potentiation (LTP) at parallel fiber …