Unlike CMT1, which results from damage to the myelin sheath insulating axons, CMT2 is caused by direct damage to nerve axons themselves. CMT2 is commonly referred to as “axonal” CMT. …

1998年9月28日 · Traditional classification of CMT (e.g., CMT1, CMT2, and DI-CMT [dominant intermediate]) was based on peripheral neuropathy type as determined by nerve conduction …

Electrodiagnostical studies show a length-dependent motor and sensory axonal dysfunction in both CMT-types. Additional SNAP and SNCV evaluation may be helpful in focusing molecular …

CMT2 is not as common as CMT1, but has similar symptoms. Rather than damaging the nerves’ insulating myelin sheath, CMT2 affects the axon. Because of this CMT2 is also known as …

Charcot-Marie-Tooth病有几种类型，它们通过对神经细胞和遗传模式的影响而有所区别。 1型（CMT1）的特征是 髓鞘 异常，这种脂肪物质覆盖神经细胞，保护它们并帮助传递神经冲动 …

2018年10月8日 · Results: The CMT1 group was significantly greater for age, height and body mass in comparison to the CMT2 group (Table 1). The CMT1 group also showed significantly …

Whereas the original descriptions of CMT2 identified patients affected at an older than typical CMT1 patients, the mutations that cause these late onset cases have proven difficult to …

2021年12月10日 · CMT2 is less common than CMT1, accounting for about 12% to 36% of all CMT cases. CMT2 has been further subdivided into subtypes based on which genes are …

2007年1月1日 · To evaluate the clinical and electrophysiological similarities and differences between two large groups of patients with Charcot-Marie-Tooth disease, i.e. CMT1A and …

CMT that directly damages the peripheral nerve axon is known as axonal CMT (Type 2). When CMT directly damages the peripheral nerve axon, the speed at which the nerve transmits a …