2024年12月24日 · CNTN1 (Contactin 1) is a Protein Coding gene. Diseases associated with CNTN1 include Congenital Myopathy 12 and Congenital Lethal Myopathy, Compton-North Type. Among its related pathways are NOTCH2 Activation and Transmission of Signal to the Nucleus and Nervous system development.

Contactin 1 (CNTN1) is a protein which in humans is encoded by the CNTN1 gene. [5] [6]

Cntn1, a subset of the neural cell adhesion protein and immunoglobulin supergene family, participates in cell contact formation and axonal growth control and plays a role in degenerative and inflammatory disorders.

Accumulating evidence from recent years suggest Contactin 1 (CNTN1)’s possession of multiple oncogenic activities in a variety of cancer types. CNTN1 is a cell adhesion molecule that is dysregulated in many human carcinomas and plays important roles in …

Contactin-1 (CNTN1) antibody-positive nodopathy is rare and exhibits distinct clinical symptoms such as tremors and ataxia. However, the mechanisms of these symptoms and the characteristics of the cerebral spinal fluid (CSF) remain unknown.

CNTN1 is a new gene which can be regulated by RET/PTC3 (Ret proto-oncogene and Ret-activating protein ELE1) rearrangement gene and the protein level of CNTN1 is increasing in thyroid cancer. Structurally, CASPR2 is highly glycosylated …

Title: Key Molecules in Bladder Cancer Affect Patient Prognosis and Immunotherapy Efficacy: Further Exploration for CNTN1 and EMP1. Contactin-1 links autoimmune neuropathy and membranous glomerulonephritis.

2023年12月3日 · CNTN1 contactin 1 Gene ID: 1272, updated on 3-Dec-2023 Gene type: protein coding Also known as: F3; GP135; MYPCN; CMYP12. See all available tests in GTR for this gene; Go to complete Gene record for CNTN1; Go to Variation Viewer for CNTN1 variants; Summary. The protein encoded by this gene is a member of the immunoglobulin superfamily.

CNTN1 is relatively higher expressed in coronary artery disease than in normal samples. CNTN1 has been identified as a co-pathogenic target gene in both coronary artery disease and pulmonary arterial hypertension. Diagnostic value has been detected in CNTN1 for coronary artery disease.

2024年4月11日 · Electrophysiologic analysis showed that Cntn1 -/- mice had decreased peripheral nerve conduction velocity and excitability. Boyle et al. (2001) concluded that formation of paranodal junctions depends on CNTN1-mediated signals that also maintain the electrophysiologic properties of peripheral nerves.