Codium cell wall polysaccharides, eg, sulfated galactans, sulfated arabinans, mannans, and hydroxyproline-rich glycoproteins, result in distinct structural features, several of them exhibiting biological activities with pharmaceutical applications, eg, anticoagulants, antiangiogenics, antivirals, and immunostimulants (Fernández et al., 2014).

Codium is a genus of edible green macroalgae (or seaweed) under the order Bryopsidales. The genus name is derived from a Greek word that pertains to the soft texture of its thallus.

2020年12月8日 · In this study, we examined the effect of Codium fragile polysaccharide (CFP) on natural killer (NK) cell activation, and its effect on tumor-bearing mice. Intravenous CFP treatment of C57BL/6 mice resulted in the upregulation of CD69, …

Compounds obtained from Codium have demonstrated significant biological activities, such as immunostimulatory, anticoagulant, anticancer, anti-inflammatory, antioxidant, antiviral, antibacterial, antifungal, antitumor, anti-angiogenic, osteoprotective, and anti-obesity activities.

2020年10月27日 · In this study, we found that CFP promoted the upregulation of CD80, CD83 and CD86 and major histocompatibility complex (MHC) class I and II in human monocyte-derived dendritic cells (MDDCs). In addition, CFP induced the …

In this study, anionic macromolecules extracted from Codium fragile were investigated for their cooperative immune-enhancing activities with ARA. The cooperation between ARA and Codium resulted in increased, dose-dependent nitric oxide production and iNOS gene expression.

2020年10月27日 · DCs are the most powerful antigen-presenting cells that induce T cell immunity [17, 18]. Activation of DCs is defined by the upregulation of co-stimulatory molecules, presentation of antigens by major histocompatibility complex (MHC) proteins, and production of cytokines [5].

Cell walls in this seaweed are highly complex structures composed of 31% (w/w) of linear (1→4)-β-d-mannans, 9% (w/w) of pyruvylated arabinogalactan sulfates (pAGS), and low...

2000年5月1日 · Salinity limits plant growth and impairs agricultural productivity. There is a wide spectrum of plant responses to salinity that are defined by a range of adaptations at the cellular and the whole-plant levels, however, the mechanisms of sodium transport appear to be fundamentally similar.

Codium fragile is a green alga of Codiales family and has been reported to exhibit anti-edema, anti-allergic, anti-protozoal and anti-mycobacterial activities. In this study, we have investigated a novel anti-inflammatory potential of C. fragile using in …