Cornea verticillata (also called vortex keratopathy, whorl keratopathy, or Fleischer vortex) describes a whorl-like pattern of golden brown or gray opacities in the corneal epithelium. It is termed cornea verticillata from the Latin noun “verticillus,” meaning "whorl”.

Cornea verticillata, also called vortex keratopathy or whorl keratopathy, is a condition characterised by corneal deposits at the level of the basal epithelium forming a faint golden-brown whorl pattern. [2] It is seen in Fabry disease or in case of prolonged amiodarone intake. [3]

Corneal disease: The classic and most common presentation of corneal disease involves the presence of cornea verticillata. Verticillata can be observed stemming from the central cornea as opacified, snaking lines. [3]

Cornea verticillata also called vortex keratopathy, whorl keratopathy or Fleischer vortex, describes a whorl-like pattern of golden brown or gray opacities in the cornea.

Some of the most commonly recognised drug-related corneal deposits produce a vortex keratopathy, or corneal verticillata, a whorl-like opacity in the corneal epithelium.

The most well-known condition caused by drug deposits is vortex keratopathy, or corneal verticillata, which is a whorl-like opacity in the corneal epithelium. Vortex keratopathy is commonly caused by certain cationic amphiphilic drugs such as amiodarone, antimalarials, suramin, tamoxifen, chlorpromazine and non-steroidal anti-inflammatory drugs.

Cornea verticillata, also known as vortex keratopathy, describes a pattern of whorl- shaped opacities within the basal corneal epithelium. They are most commonly located in the inferior paracentral region, are non-elevated, and can range from white to brown in color.

2023年10月17日 · Cornea verticillata, also known as vortex keratopathy or whorl-like corneal deposits, is a benign and asymptomatic corneal condition characterized by distinctive whorl-like patterns of tiny brownish or golden-brown deposits on the corneal surface.

Cornea verticillata, visible with slit-lamp microscopy, is the most distinctive and common ocular finding in Fabry disease, and is present in the majority of male and female patients as well as asymptomatic female carriers. Note the radial, spoke-like lines emerging from a single vortex. Radial lines can range in color from white to golden brown.

The signature ocular manifestation is the whorl-like corneal pattern of lipid (glycosphingolipid) deposits which are present in both hemizygous males and heterozygous females. These are sometimes referred to as cornea verticillata or Fleischer vortex dystrophy with a pattern similar to that seen in some patients using atabrine or amiodarone.