2006年11月2日 · Neurogenesis within the adult central nervous system is demonstrated using an exogenous cell tracer, 5'-bromo-2'-deoxyuridine (BrdU), in combination with endogenous …

In this study, we labeled the proliferative reactive astrocytes with BrdU in the mouse motor cortex after ischemic insult, then used NeuroD1 to induce AtN conversion. When we examined the …

Here, using the embryonic mouse cerebral cortex as a model system, we describe a simplified dual thymidine analogue protocol using BrdU and EdU that can be used to measure T s and T …

1988年8月2日 · The use of an exogenously administered thymidine analog, 5-bromo-2′-deoxyuridine (BrdU), for studies of the proliferation, migration and time of origin of cells in the …

2007年1月1日 · BrdU immunohistochemistry has been instrumental to confirm that neurogenesis occurs in the adult mammalian brain, including in human. BrdU may be delivered by …

2017年7月21日 · Neurogenesis from Sox2 + cells in the adult cerebellar cortex. Combined BrdU birth-dating and fate-mapping experiments show RFP + progeny from Sox2 + cells (a) that had …

In the present study, we found that: 1) cells in the injured ipsilateral SVZ present obvious BrdU immunoreactivity, indicating SVZ cell proliferation after cerebral cortex excision in the adult …

Mechanistic studies reveal that RAB39b interacts with PI3K components and its deletion promotes PI3K–AKT–mTOR signaling in NPCs of mouse cortex and cerebral organoids. The mTOR …

1988年8月2日 · The use of an exogenously administered thymidine analog, 5-bromo-2'-deoxyuridine (BrdU), for studies of the proliferation, migration and time of origin of cells in the …

The synthetic halogenated pyrimidine analog, 5-bromo-2′-deoxyuridine (BrdU), is a marker of DNA synthesis. This exogenous nucleoside has generated important insights into the cellular …