Soluble microneedles developed by the proprietary technology of CosMED Pharmaceutical is a sheet formed by an array of microneedles, which have a height of several dozen to several hundred micrometers depending on use, with a mixture containing highly biocompatible macromolecular hyaluronic acid as a base component and drugs or active ingredients.

The microneedle technology provides a new patch type transdermal absorptive drug that administers a drug into the body by applying a skin patch of microneedles containing the drug on their tips.

2022年4月26日 · 经过两年的探索，Cosmed成功开发出了肉眼几乎不可见的超微细针中的“可溶性微针”技术。 该系统将以皮肤中天然存在的透明质酸为原料的微针粘贴在皮肤上，便能将高分子成分释放到皮肤内。

マイクロニードルは、長さ数百ミクロンの微細な針で、皮膚から薬剤や有効成分を吸収させる技術。 薬剤を皮膚に塗布するより、効率的で多量の成分を送達させることが可能です。 医療・医薬領域では、痛みがなく、簡便に薬剤を体内に吸収させる「注射に代わる薬剤投与技術」として、ワクチン投与などへの応用が期待されています。 コスメディ製薬は、ヒアルロン酸やコラーゲンなど「皮膚に含まれる成分」でできた針が皮膚内で溶ける「溶解型マイクロニードル」の …

2019年1月1日 · Researchers have developed a refined technology using microneedles, which allow hydrophilic high molecular weight compounds to enter into the stratum corneum. Administration of drugs using the microneedle device allows the drug molecules to cross the stratum corneum layer, thus allowing more drug molecules to enter the skin.

Transcutaneous immunization (TCI) is an attractive vaccination method compared with conventional injectable vaccines because it is easier to administer without pain. We developed a dissolving microneedle patch (MicroHyala, MH) made of hyaluronic acid and showed that transcutaneous vaccination using …

2024年1月1日 · Integrated microneedle roller comes in six different models of different lengths for personal, clinical and medical use, specifically used for cosmetic purposes, such as, skin restoration, improve alopecia, skin whitening, collagen induction, improve wrinkle, cellulite treatment, and drug delivery [139].

CosMED Pharmaceutical was founded in 2001, the company specializes in the development, manufacturing and sales of transdermal drug delivery system and skin care products. The manufactured microneedle cosmetics was the world’s first launched product in 2008.

“Representative ones of our microneedle patch products that embody our unique TTS technology with a high-density needles and well selected ingredients. Eye area and mouth area are available and they help to improve the appearance of fine lines and wrinkles. Dermafiller Premier for eye : 1 pair JPY2,000. Excluding Tax (MSRP in Japan) 4 pairs ...

As a new method of DDS (drug delivery system) to release beauty ingredients into the skin, for the first time in the world, we have succeeded in developing and commercializing the “soluble microneedle cosmetics” that enables to release macromolecular active ingredients into the skin easily and safely by simply pasting microneedles made of ...