The Carr-Purcell-Meiboom-Gill sequence (CPMG) experiment allows to measure transverse or spin-spin T 2 relaxation times of any nucleus. The experimental half-height linewidth (d) of a given resonance is directly related to T 2 * by the equation d=1/(pi*T 2 *)

Different methods have been used to suppress the water signal, including 1D Carr–Purcell–Meiboom–Gill (CPMG) presat, consisting of a T2 filter to suppress macromolecule signals and reduce the humped curve in the spectrum. 1D nuclear Overhauser enhancement spectroscopy (NOESY) is another method for water suppression that is used routinely in plan...

2023年6月26日 · Preferred 1D methods for 1H NMR-based metabolomics include 1D 1H nuclear Overhauser effect spectroscopy (NOESY) presat pulse sequence, Carr−Purcell−Meiboom− Gill (CPMG) presat (T 2 filter),56,57 1D 1H presat, and 1D 1H excitation sculpting (ES) with gradients.58 Despite the utility for 1D 1H NMR of the firsttwo methods, the pulse sequences

The Carr-Purcell-Meiboom-Gill (CPMG) Sequence is a pulse sequence in NMR spectroscopy that involves a series of 180° pulses applied to transverse magnetization to enhance signal detection and reduce decoherence effects. AI generated definition based on: Methods in Enzymology, 2019

Different methods have been used to suppress the water signal, including 1D Carr–Purcell–Meiboom–Gill (CPMG) presat, consisting of a T2 filter to suppress macromolecule signals and reduce the humped curve in the spectrum. 1D nuclear Overhauser enhancement spectroscopy (NOESY) is another method for water suppression that is used routinely in pla...

The recent 1D methods based on the CWFP regime or the low-power CPMG sequence have potential as alternatives to CPMG to enhance SNR and resolution and minimize instrumental or sample-heating problems, especially when fast analysis protocols are …

2023年1月31日 · The most common method of removing macromolecular signals from biofluid NMR spectra is relaxation editing, most notably using the 1D CPMG spin–echo experiment, which is frequently used in the metabolic profiling analysis of blood plasma and serum samples.

在研究生物大分子动态性方面比较常用的方法是CPMG（Carr–Purcell–Meiboom–Gill）和R1ρ。 这两种实验在磁化矢量的初始状态、所使用的RF脉冲类型、测量的策略等方面都有所不同。

2020年9月14日 · Two sets of one-dimensional 1 H NMR experiments were performed for all the samples analysed: CPMG spin-echo with and without water presaturation and one single-pulse 1 H NMR experiments, recorded over a spectral width of 20 ppm with a free induction decay (FID) acquired into 64 K data points during a 2.7 s acquisition time. Thirty-two scans ...

2024年11月1日 · The CPMG filter is an NMR building block that can be incorporated within a 1D 1 H NMR pulse sequence with or without solvent suppression. As the name says, it acts as a filter, removing molecules with short T 2 relaxation values of a few milliseconds or less from the 1D NMR spectrum and observing only molecules with long T 2 relaxation values ...