CRBN (D8H3S) Rabbit mAb | Cell Signaling Technology
1 天前 · CRBN (D8H3S) Rabbit mAb recognizes endogenous levels of total CRBN protein. Human, Mouse, Rat. Monoclonal antibody is produced by immunizing animals with a synthetic …
CRBN antibody (28494-1-AP) | Proteintech - ptglab
CRBN is also identified as important thalidomide-binding protein for limb outgrowth in zebrafish and chicks. It can be detected a band above 51 kDa (maybe 55 kDa) in HT22 cells (PMID: …
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Molecular glue CELMoD compounds are regulators of cereblon
2022年11月3日 · CRBN is a 50-kDa protein containing three folded domains: an N-terminal Lon protease-like domain (hereafter, Lon domain), an intermedial helical bundle (HB), and a C …
CRBN (D8H3S) Rabbit mAb #71810 - Cell Signaling Technology …
CRBN (D8H3S) Rabbit mAb recognizes endogenous levels of total CRBN protein. Human, Mouse, Rat. Monoclonal antibody is produced by immunizing animals with a synthetic peptide …
Anti-CRBN抗体[4D6] (ab244223) - Abcam中文官网
In Western blot, ab244223 was shown to bind specifically to CRBN. A band was observed at 51 kDa in wild-type MCF7 cell lysates with no signal observed at this size in CRBN knockout cell …
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An engineered cereblon optimized for high-throughput screening …
2025年2月20日 · We show this applicability here through development of the “Enamine CRBN focused IMiD library” of 4480-IMiD based derivatives and application of our CRBN construct in …
Science | 靶向蛋白降解途径突破，几乎可用于任何疾病相关蛋白
2022年11月22日 · CRBN （cereblon）是CRL4CRBN E3连接酶复合物的底物识别亚单位。 Scripps Research的科学家们发现了一种有前途的新型抗癌药物 CELMoDs 的一个关键特性。 …
CRBN配体的作用和最新进展 - 知乎
它们被称为cereblon（CRBN）E3连接酶调节剂（CELMoD）或者免疫调节药物（IMiDs），与CRBN结合，CRBN与 DDB1 (damaged DNA binding protein 1)、Cul4A (Cullin 4A)、ROC1 …
Targeting cereblon in hematologic malignancies - ScienceDirect
2023年1月1日 · The protein cereblon (CRBN) is a substrate receptor of the cullin 4-really interesting new gene (RING) E3 ubiquitin ligase complex CRL4 CRBN. Targeting CRBN …
CRBN (D8H3S) Rabbit mAb (BSA and Azide Free) #46351
CRBN (D8H3S) Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total CRBN protein. Human, Mouse, Rat. Monoclonal antibody is produced by immunizing animals with a …