
Collapsin response mediator protein family - Wikipedia
Collapsin response mediator protein family or CRMP family consists of five intracellular phosphoproteins (CRMP-1, CRMP-2, CRMP-3, CRMP-4, CRMP-5) of similar molecular size …
脑衰反应调节蛋白2(collapsin response mediator protein 2, CRMP2)最先是作为轴突导向因子Sema3A通路的下游信号被发现,其靶结构为细胞骨架,通过与微管蛋白二聚体的相互作用调节 …
CRMP2可通过改善神经细胞凋亡减轻缺血/再灌注大鼠神经功能缺损
CRMP2 (collapsin response mediator protein 2)是胞质磷酸化蛋白CRMP1-5家族成员之一,可参与调解多种神经生理活动,如:微管动力学、轴突出芽及回缩、神经分化、树突/轴突特化、 …
CRMP-2 binds to tubulin heterodimers to promote microtubule
2002年7月15日 · Collapsin response mediator protein-2 (CRMP-2) is a mammalian homologue of UNC-33, mutations in which result in abnormal axon termination. We recently demonstrated …
Collapsin response mediator protein 2: high-resolution crystal
Collapsin response mediator protein 2 (CRMP-2) is a neuronal protein involved in axonal pathfinding. Intense research is focusing on its role in various neurological diseases. Despite a …
CRMP2: functional roles in neural development and therapeutic ... - PubMed
Collapsin response mediator protein 2 (CRMP2) has long been identified as a microtubule-binding protein that regulates neuronal polarity in vitro. Recent studies provide new insights into the …
Phosphorylated tubulin adaptor protein CRMP-2 as prognostic ... - PubMed
2013年5月1日 · Collapsin response mediator protein-2 (CRMP-2) is the first described and most studied member of a family of proteins that mediate the addition of tubulin dimers to the …
GSK-3β Regulates Phosphorylation of CRMP-2 and Neuronal …
2005年1月14日 · We previously showed that collapsin response mediator protein-2 (CRMP-2) is critical for specifying axon/dendrite fate, possibly by promoting neurite elongation via …
胶原蛋白介导蛋白2:高分辨率的晶体结构揭示了小分子结合,翻 …
胶原蛋白介导蛋白2(crmp-2)是一种神经元蛋白,参与轴突寻路。 激烈的研究集中在其在各种神经系统疾病中的作用。 尽管进行了大量研究,但关于CRMP-2体内功能的分子机制知之甚少。
CRMP-2 regulates polarized Numb-mediated endocytosis for …
2003年8月24日 · Previously, we demonstrated that collapsin response mediator protein-2 (CRMP-2) is critical for specifying axon/dendrite fate and axon growth in cultured hippocampal …