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Cathepsin B - Wikipedia
Cathepsin B is synthesized on the rough endoplasmic reticulum as a preproenzyme of 339 amino acids with a signal peptide of 17 amino acids. [14] [15] Procathepsin B of 43/46 kDa is then …
Cathepsin B Gene Knockout Improves Behavioral Deficits and …
Cathepsin B (CTSB) is a powerful lysosomal protease. This review evaluated CTSB gene knockout (KO) outcomes for amelioration of brain dysfunctions in neurologic diseases and …
The Role of Cathepsin B in Pathophysiologies of Non-tumor and …
Role of CTSB in cell death. In the presence of LMP, CTSB is released into the cell matrix, leading to lysosome-dependent death, and triggers the activation of the apoptotic cascade by …
CTSB Gene - GeneCards | CATB Protein | CATB Antibody
2024年12月24日 · CTSB (Cathepsin B) is a Protein Coding gene. Diseases associated with CTSB include Keratolytic Winter Erythema and Hyperparathyroidism, Neonatal Severe.Among its …
Cathepsin B: The dawn of tumor therapy - ScienceDirect
2024年4月5日 · Cancer remains the major threat to human health, with 19.3 million new cancers and approximately 10 million deaths in 2020 alone [1].CTSB is a lysosomal cysteine protease …
CTSB is a negative prognostic biomarker and therapeutic target ...
2022年3月11日 · CTSB is remarkably highly-expressed in HGG, isocitrate dehydrogenase (IDH) wildtype, 1p19q non-codeletion type and O 6-methylguanine-DNA methyltransferase (MGMT) …
CTSB cathepsin B [Homo sapiens (human)] - Gene - NCBI
2025年2月9日 · Official Symbol CTSB provided by HGNC Official Full Name cathepsin B provided by HGNC Primary source HGNC:HGNC:2527 See related Ensembl:ENSG00000164733 …
Cathepsin B in cardiovascular disease: Underlying mechanisms and ...
Cathepsin B (CTSB) is a member of the cysteine protease family, primarily responsible for degrading unnecessary organelles and proteins within the acidic milieu of lysosomes to …
1508 - Gene ResultCTSB cathepsin B [ (human)] - National Center …
This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein …