2024年12月24日 · CUL5 (Cullin 5) is a Protein Coding gene. Diseases associated with CUL5 include Molluscum Contagiosum and Autism Spectrum Disorder. Among its related pathways …

Cullin-5 is a protein that in humans is encoded by the CUL5 gene. [5][6][7] The mammalian gene product was originally discovered by expression cloning, due to the protein's ability to mobilize …

2024年1月19日 · Here authors identify Cul5, a ubiquitin E3 ligase as an important inhibitor of CD8 + T cell anti-tumour cytotoxicity and persistence via involvement with both T cell receptor and …

2020年12月1日 · Cullin-RING ligase 5 (CRL5) is a multi-protein complex and consists of a scaffold protien cullin 5, a RING protein RBX2 (also known as ROC2 or SAG), adaptor …

2022年5月19日 · Here, we show that the E3 ubiquitin ligase Cul5 determines fate selection in CD4 + T cells by regulating IL-4 receptor signaling. Mice lacking Cul5 in T cells develop Th2 …

2024年12月10日 · We find that genetic ablation of CUL5, encoding a core element of the multi-protein E3 ubiquitin-protein ligase complex, cullin-RING ligase 5, enhances human CD19 CAR …

2016年3月9日 · Here, we review the current knowledge on the identification of Cul5 and the regulation of its expression, as well as the signaling pathways regulated by Cul5 and how …

Here using mouse models we find that Cullin5 (CUL5), a key component of Cullin-RING E3 ubiquitin ligase 5, is upregulated and associated with increased neutrophil count and influenza …

Cullin-RING ligase 5 (CRL5) is a multi-protein complex and consists of a scaffold protien cullin 5, a RING protein RBX2 (also known as ROC2 or SAG), adaptor proteins Elongin B/C, and a …

最近，有研究人员报道了E3连接酶亚单元Cullin 5（CUL5）的缺失能够促进染色体的不稳定性，并且可以作为ccRCC的一个独立的阴性预后因素。 研究人员指出，CUL5最初是从RNA干扰筛选 …