A light cascade-enhanced synergistic PTT/PDT/CDT was achieved by Yang et al. using the cyclen-Cu 2+ complexes, where tumor-derived H 2 S reacted with Cu 2+ to generate CuS for PTT and release Ce6 for PDT. The intracellular hypoxic stress was amplified to trigger AQ4N-associated CDT, resulting in a light cascade-enhanced synergistic PTT/PDT/CDT.

2024年5月25日 · The CuS@Rutin demonstrated the dual functionality of PTT and PDT. When subjected to near-infrared laser irradiation, it exhibited potent bactericidal effects against Escherichia coli and Staphylococcus aureus , effectively regulated ROS levels, and modulated the expression of inflammation-related cytokines, thereby alleviating local inflammation.

2017年9月1日 · Photodynamic therapy (PDT) and photothermal therapy (PTT) have been emerging as attractive and promising methods for tumor treatment in clinical approaches. CuS nanoparticles are effective and cost-effective agents for PTT. Recently, it was observed that CuS nanoparticles are also excellence candidates for PDT.

Photodynamic therapy (PDT) and photothermal therapy (PTT) have been emerging as attractive and promising methods for tumor treatment in clinical approaches. CuS nanoparticles are effective and cost-effective agents for PTT.

2023年11月21日 · As a PTT/PDT combination therapeutic platform, CuS@COF nanosheets possess a porous TP–BDT-based COF shell, and it can sufficiently contact oxygen to provide high singlet oxygen (1 O 2) yield under 505 nm laser irradiation. Upon illumination with a 1064 nm laser, CuS@COF nanosheets can effectively convert the photon energy into thermal energy ...

光热治疗 （PTT）是一种利用NIR光吸收剂吸收近红外光后产生的热量来消融癌细胞的治疗方法。 CuS纳米粒子具有近红外光学性能良好，细胞毒性小等优点，其 局域表面等离子体共振 可以将接收到的光能转化为热能，因而作为一种新型光热剂受到了研究者的广泛关注。 ACS Nano报道了一种由碳点、CuS纳米颗粒组成的空心结构CuSCDs，该颗粒在808纳米的激光照射下表现出优异的光热转换效率。 在加载蛋白酶体抑制剂的CuSCD表面涂上杂交有T7肽的巨噬细胞膜 …

This review focuses on copper sulfide (CuS) nanomaterials as efficient and cost-effective PDT and PTT therapeutic nanomaterials with antibacterial activity. The features and merits of CuS nanomaterials as therapeutics are compared to those of other nanomaterials.

2023年6月10日 · Herein, we constructed a chemical-NIR dual-propelled nanomotor based on CuS/Pt Janus nanoparticles with IR820 encapsulation for hypoxia alleviation, deep tumor penetration and augmented synergistic photodynamic (PDT) and photothermal therapy (PTT).

这里的目标是探索cus纳米颗粒作为ptt和pdt试剂的杀灭机制。 通过简单的湿化学方法，用两亲性聚合物包被，合成CuS纳米颗粒，并在体外和体内检查其对肺腺癌细胞SPC-A-1的治疗潜力使用鼠类癌症模型。

2023年12月14日 · As a PTT/PDT combination therapeutic platform, CuS@COF nanosheets possess a porous TP-BDT-based COF shell, and it can sufficiently contact oxygen to provide high singlet oxygen (1 O 2) yield under 505 nm laser irradiation. Upon illumination with a 1064 nm laser, CuS@COF nanosheets can effectively convert the photon energy into thermal energy ...