Endothelial cell-specific knockout of connexin 43 causes …
Here, we report the generation and characterization of a vascular endothelial cell-specific deletion of the Cx43 gene (VEC Cx43 KO) in mice by using the loxP/Cre system. Using homologous …
Connexin 43 is required for the maintenance of mitochondrial …
2017年8月2日 · We investigated the role of connexin 43 (Cx43) in maintaining the integrity of mitochondria in brown adipose tissue (BAT). The functional effects of Cx43 were evaluated …
Endothelial cell-specific knockout of connexin 43 causes ... - PNAS
2001年7月31日 · Here, we report the generation and characterization of a vascular endothelial cell-specific deletion of the Cx43 gene (VEC Cx43 KO) in mice by using the loxP/Cre system. …
Injury Induced Connexin 43 Expression Regulates Endothelial …
2025年2月24日 · We show significantly delayed EC healing in a mouse model of inducible EC-specific Cx43 deletion (EC-Cx43 KO) at 24 hr post ligation. Single cell RNAseq analysis of …
Endothelial cell-specific knockout of connexin 43 causes
2001年8月14日 · Cx43-null mice die shortly after birth, thus preventing functional studies in vivo. Here, we report the generation and characterization of a vascular endothelial cell-specific …
Effects of a Sertoli cell-specific knockout of Connexin43 on …
2023年11月1日 · Adult male Sertoli cell-specific Connexin43 knockout mice (SCCx43KO) exhibit higher Sertoli cell (SC) numbers per seminiferous tubule compared to their wild type (WT) …
Connexin43 Modulates Cell Polarity and Directional Cell Migration …
2011年10月14日 · Studies using embryonic fibroblasts from Cx43 knockout (Cx43KO) mice showed Cx43 deficiency caused cell polarity defects as characterized by a failure of the Golgi …
A Sertoli Cell-Specific Knockout of Connexin43 Prevents Initiation …
2007年7月1日 · The present study demonstrates the generation of a conditional cx43-KO mouse line lacking a functional cx43 gene solely in SCs. Successful deletion of the cx43 gene was …
Connexin 43 regulates epicardial cell polarity and migration in ...
2009年9月9日 · Connexin 43 knockout (Cx43 KO) mice exhibit conotruncal malformations and coronary artery defects. We observed epicardial blisters in the Cx43 KO hearts that suggest …
C-Terminal Truncation of Connexin43 Changes Number, Size, …
2007年10月11日 · Haplodeficient mice expressing carboxyl-terminally truncated Cx43 (K258stop/KO), instead of the wild-type Cx43 isoform, reach adulthood and reveal no …