2024年12月25日 · MT-CYB (Mitochondrially Encoded Cytochrome B) is a Protein Coding gene. Diseases associated with MT-CYB include Cardiomyopathy, Infantile Histiocytoid and Leber Hereditary Optic Neuropathy, Modifier Of.

Its gene product is a subunit of the respiratory chain protein ubiquinol–cytochrome c reductase (UQCR, complex III or cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MT-CYB (mitochondrial cytochrome b), and ten nuclear genes— UQCRC1, UQCRC2, CYC1, UQCRFS1 (Rieske protein), UQCRB, "11kDa protein ...

The MT-CYB gene provides instructions for making a protein called cytochrome b. This protein plays a key role in structures called mitochondria, which convert the energy from food into a form that cells can use. Learn about this gene and related health conditions.

Variations in mitochondrial DNA (mtDNA) cytochrome b (mt‐cyb) are frequently found within the healthy population, but also occur within a spectrum of mitochondrial and common diseases. mt‐cyb encodes the core subunit (MT‐CYB) of complex III, a central component of the oxidative phosphorylation system that drives cellular energy production and ho...

A particularly interesting HCM mtDNA candidate gene is MT-CYB, coding for cytochrome b (Cytb), a component of complex III (CIII). Missense mutations in this gene have been associated with several diseases with cardiac and muscular involvement, including HCM (Valnot et al. 1999; Andreu et al. 2000; http://mitomap.org 2012).

2025年2月8日 · Gene target information for CYTB - cytochrome b (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Cytochrome b (MTCYB) is the only mitochondrial DNA (mtDNA) encoded subunit of respiratory Complex III (ubiquinol:ferrocytochrome c oxidoreductase, or cytochrome bc1, complex, EC 1.10.2.2).

To date, more than 350 genes in both mitochondrial and nuclear genomes are known to cause primary mitochondrial diseases [4]. In the present review we will give an overview of the principal molecular genetic defects linked to PMM (Table 1).

Cytochrome b (CYB) protein plays an important role in complex III of the mitochondrial oxidative phosphorylation. Codon usage is the phenomenon of non-uniform usage of synonymous codons. In the present study, we report the pattern of codon usage in MT-CYB gene using various codon usage parameters. N …

Association between the single nucleotide variants of the mitochondrial cytochrome B gene (MT-CYB) and the male infertility. Liver mitochondrial DNA damage and genetic variability of Cytochrome b - a key component of the respirasome - drive the severity of fatty liver disease.