Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization.

2024年12月24日 · CCNB2 (Cyclin B2) is a Protein Coding gene. Diseases associated with CCNB2 include Adrenocortical Carcinoma and Breast Cancer. Among its related pathways are Loss of proteins required for interphase microtubule organization from …

Cyclin是一类能够周期性地表达和降解的蛋白质，通过与 周期蛋白依赖性激酶 （CDKs）组成复合物，在细胞周期的不同阶段起着关键的调控作用。

There are two different cyclin B proteins in mammalian cells. Cyclin B2 is a non-essential protein that associates with the Golgi apparatus and probably plays a role in Golgi remodelling during mitosis [10,11]. Cyclin B1 is an essential protein that is thought to be responsible for most of the other actions of Cdk1 in the cytoplasm and nucleus ...

Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery.

2025年2月9日 · Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization.

2012年2月7日 · Cyclin B2 is a protein that, when overexpressed, is strongly associated with the development of certain tumors like colon and lung cancer. It plays a role in chromosome segregation errors and is required for inducing aneuploidy via …

Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within several processes, including T cell homeostasis; meiosis I cell cycle process; and thymus development. Located in cytoplasm and membrane.

Cyclin B2 是促有丝 分裂因子MPF 的重要组成之一，cyclin B2 表达的 抑制会影响MPF 的活性，从而使细胞周期G2/M 期的进程和细胞的有丝分裂受到抑制。

Data show that the cyclin B2 was overexpressed in bladder cancer tissue. Cyclin B1 and cyclin B2 are interchangeable for ability to promote G2 and M transition in HeLa cells. Suggest that cytoplasmic CCNB2 may function as an oncogene and could serve as a potential biomarker of unfavorable prognosis over short-term follow-up in breast cancer.