2024年12月24日 · CYP26C1 (Cytochrome P450 Family 26 Subfamily C Member 1) is a Protein Coding gene. Diseases associated with CYP26C1 include Focal Facial Dermal Dysplasia 4 and Ectodermal Dysplasia/Skin Fragility Syndrome. Among its related pathways are Oxidation by cytochrome P450 and Signaling by Retinoic Acid.

CYP26C1 (cy tochrome P 450, family 26, subfamily c, polypeptide 1) is a protein which in humans is encoded by the CYP26C1 gene. [5] This gene encodes a member of the cytochrome P450 superfamily of enzymes.

2025年2月8日 · findings suggest that CYP26C1 is a 4-oxo-atRA hydroxylase and may be important in regulating the concentrations of this active retinoid in human tissues; Together, these findings describe CYP26C1 as the first genetic modifier for SHOX deficiency. Elevated expression of CYP26C1 in primary breast carcinomas

2023年11月23日 · Clinical resource with information about CYP26C1, Focal facial dermal dysplasia type IV, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

The Cytochrome P450 (CYP) family 26 enzymes contribute to retinoic acid (RA) metabolism and homeostasis in humans, mammals and other chordates. The three CYP26 family enzymes, CYP26A1, CYP26B1 and CYP26C1 have all been shown to metabolize all-trans-retinoic acid (atRA) it's 9-cisRA and 13-cisRA isom …

该基因编码细胞色素 P450 酶超家族的成员。 细胞色素 P450 蛋白是单加氧酶，可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。 这种酶参与全反式和 9-顺式视黄酸的分解代谢，因此有助于调节细胞和组织中的视黄酸水平。 该基因与染色体 10q23.33 上的相关基因相邻。 [RefSeq 提供，2008 年 7 月] This gene encodes a member of the …

2024年12月27日 · 本文将详细介绍CYP26C1基因及其相关的疾病，该基因位于10q23.33，属于Cytochrome P450家族26亚家族C成员1，编码一个具有蛋白质产物的基因。 了解CYP26C1基因 CYP26C1基因，听起来是不是有点复杂？

In the regenerating lateral line upregulation of raldh3, rarβ and cyp26a1 followed by cyp26c1, is rapidly and transiently induced. Cyp26a1 expression restricted to two cells adjacent to the neuromasts and cyp26c1 is mostly seen in the dorsoventral poles of the neuromast.

The deduced 522-amino acid protein contains a heme thiolate benchmark motif characteristic of all cytochrome p450s. CYP26C1 shares 43% amino acid identity with CYP26A1 (602239) and 51% amino acid identity with CYP26B1 (605207). PCR analysis detected CYP26C1 expression in most tissues at low levels.

2004年1月2日 · In this report, we describe the identification, molecular cloning, and substrate characterization of a third member of the CYP26 family, named CYP26C1. Transiently transfected cells expressing CYP26C1 convert atRA to polar water-soluble metabolites similar to those generated by CYP26A1 and -B1.