Mar 30, 2025 · CYP26C1 (Cytochrome P450 Family 26 Subfamily C Member 1) is a Protein Coding gene. Diseases associated with CYP26C1 include Focal Facial Dermal Dysplasia 4 …

CYP26C1 (cy tochrome P 450, family 26, subfamily c, polypeptide 1) is a protein which in humans is encoded by the CYP26C1 gene. [5] This gene encodes a member of the cytochrome P450 …

Feb 8, 2025 · findings suggest that CYP26C1 is a 4-oxo-atRA hydroxylase and may be important in regulating the concentrations of this active retinoid in human tissues; Together, these …

The Cytochrome P450 (CYP) family 26 enzymes contribute to retinoic acid (RA) metabolism and homeostasis in humans, mammals and other chordates. The three CYP26 family enzymes, …

该基因编码细胞色素 P450 酶超家族的成员。 细胞色素 P450 蛋白是单加氧酶，可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。 这种酶参与全反式和 9-顺式视黄酸的分解 …

Nov 23, 2023 · Clinical resource with information about CYP26C1, Focal facial dermal dysplasia type IV, and available tests. There are links to practice guidelines and authoritative resources …

The deduced 522-amino acid protein contains a heme thiolate benchmark motif characteristic of all cytochrome p450s. CYP26C1 shares 43% amino acid identity with CYP26A1 (602239) and …

Cyp26c1 degrades retinoic acid within the equatorial retina during later eye development. Activity of CYP26A1 and CYP26C1 is required for correct A-P patterning and production of migratory …

Jan 2, 2004 · In this report, we describe the identification, molecular cloning, and substrate characterization of a third member of the CYP26 family, named CYP26C1. Transiently …

CYP26C1 was found to effectively metabolize all-trans retinoic acid (atRA), 9-cis-retinoic acid (9-cis-RA), 13-cis-retinoic acid, and 4-oxo-atRA with the highest intrinsic clearance toward 9-cis …