2005年7月19日 · Antiphospholipid antibodies (APLAs) are proteins that may be present in the blood and may increase your risk for blood clots or pregnancy losses. If you have a history of blood clots or recurrent pregnancy losses, you may have been tested for the presence of …

2024年5月6日 · Antiphospholipid syndrome is characterized by the presence of antiphospholipid antibodies in the setting of thrombosis or pregnancy loss or complications. These antibodies are autoantibodies directed against phospholipid-binding proteins and are composed of …

2024年11月5日 · Antiphospholipid Antibody Syndrome (APLA) is an autoimmune disorder characterized by the presence of antiphospholipid antibodies, which can lead to increased risk of thrombosis and pregnancy complications. Accurate identification and understanding of patient demographics, comorbidities, and outcomes are crucial for effective management of APLA.

2018年5月23日 · The antiphospholipid syndrome is a systemic autoimmune disease defined by thrombotic or obstetrical events that occur in patients with persistent antiphospholipid antibodies. 1 Thrombotic...

Antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy complications in the presence of persistent antiphospholipid antibodies (APLA). Laboratory diagnosis of APLA depends upon the detection of a lupus anticoagulant, which ...

2019年8月11日 · This chapter reviews antiphospholipid antibody syndrome (APLA) – its features, diagnosis, and therapy. Manifestations of APLA including stroke, venous thrombosis, thrombocytopenia, and pregnancy complications are discussed.

抗磷脂抗体（anti-phospholipid antibody，APLA）指与体内不同磷脂成分发生反应的抗体。 至今应用于临床检测的有狼疮抗凝物（lupus anti-coagulant，LAC）、抗心磷脂（anti-cardiolipin，AcL）抗体两大类。

抗磷脂抗体(apla)包括抗心磷脂抗体(acpla)和狼疮抗凝物质(lac).静脉或(和)动脉血栓形成、反复自然流产及血小板减少为apla综合征的三大主征.该综合征需与sle血管炎、血栓性血小板减少性紫癜(ttp)、dic、抗血管内皮细胞抗体相关的血栓症等相鉴别.危重型进展急剧,多 ...

2023年6月1日 · Antiphospholipid antibodies (APLAs) are primarily directed toward phospholipid-binding proteins and are responsible for thrombotic events. APLAs include anti-β2Glycoprotein I (anti-β2GPI), anticardiolipin (anti-CL) antibodies, and lupus anticoagulant.

APLA Syndrome: Patients with APLA and one "major clinical criterion" are said to have "APLA syndrome." The major clinical criteria include venous or arterial thrombosis (including neurological disease such as stroke), thrombocytopenia, or frequent miscarriages. Secondary APLA syndrome is APLA plus another autoimmune disease, most commonly lupus.