The enzyme cytochrome c oxidase or Complex IV (was EC 1.9.3.1, now reclassified as a translocase EC 7.1.1.9) is a large transmembrane protein complex found in bacteria, archaea, and the mitochondria of eukaryotes.

Describe the role of cytochrome c oxidase in bacterial cells. Tell that cytochrome c oxidase is found in only certain species of bacteria and is therefore useful for bacterial species identification and characterization. Explain what being "oxidase positive" means about a bacterial species metabolism, electron transport chain, and genetics.

Cytochrome c oxidase (CcO) is the terminal oxidase of cellular respiration which reduces molecular oxygen (O 2) completely to water molecules, coupled with proton pumping [1].

酵母细胞色素c氧化酶是其人类对应物的近似模型，并提供了研究突变对酶复合物的组装，结构，稳定性和功能的影响的手段。 在临床上异类的疾病组中发现了细胞色素C氧化酶功能的缺陷。

Jan 1, 2025 · Cytochrome c oxidase (CcO) is the terminal enzyme in the electron transfer chain in mitochondria. It catalyzes the four-electron reduction of O 2 to H 2 O and harnesses the redox energy to drive unidirectional proton translocation against a proton electrochemical gradient.

Jan 1, 2003 · Cytochome c oxidase is the terminal member of the electron transport chains of mitochondria and many bacteria.

Cytochrome c oxidase is the terminal complex of eukaryotic oxidative phosphorylation in mitochondria. This process couples the reduction of electron carriers during metabolism to the reduction of molecular oxygen to water and translocation of protons from the internal mitochondrial matrix to the inter-membrane space.

The generation of cellular energy in the form of ATP occurs mainly in mitochondria by oxidative phosphorylation. Cytochrome c oxidase (CytOx), the oxygen accepting and rate-limiting step of the respiratory chain, regulates the supply of variable ATP demands in cells by “allosteric ATP-inhibition of CytOx.”

Dec 21, 2015 · Cytochrome c oxidase, the terminal enzyme in the respiratory chain, reduces molecular oxygen to water and stores the released energy through electrogenic chemistry and proton pumping across the membrane. Apart from the heme-copper binuclear center, there is a conserved tyrosine residue in the active site (BNC).

As the terminal component of the mitochondrial respiratory chain, cytochrome c oxidase plays a vital role in cellular energy transformation. Human cytochrome c oxidase is composed of 13 subunits. The three major subunits form the catalytic core and are …