2024年12月15日 · Creutzfeldt-Jakob Disease (CJD) is a sporadic, invariably fatal neurodegenerative disease attributable to misfolded Prion Protein (PrP^Sc) accumulation in the Central Nervous System of affected persons. They note that this misfolding contributes to severe neurodegeneration and progressive memory loss, finally leading to death [1].

2023年1月28日 · Creutzfeldt-Jakob (KROITS-felt YAH-kobe) disease, also known as CJD, is a rare brain disorder that leads to dementia. It belongs to a group of human and animal diseases known as prion disorders. Symptoms of Creutzfeldt-Jakob disease can be similar to those of Alzheimer's disease.

2024年5月13日 · Classic CJD is a quick-moving, always fatal disease that occurs worldwide. It affects the brain and causes dementia and other problems. CJD mostly occurs in older adults. There is no treatment or cure. It usually leads to death within a year from when symptoms begin. CJD is caused by a prion, a type of infectious protein.

2016年9月4日 · Creutzfeldt-Jakob病（CJD）是一种较为少见的神经系统变性疾病，但因其进展迅速且致死率高，准确而快速的诊断十分重要。 近期一篇综述更新了CJD的诊断标准。

Creutzfeldt-Jakob disease (CJD) is a rare, degenerative fatal brain disorder. It affects about one person in every one million people, or approximately 200 people in the United States annually. CJD usually appears later in life. Typically, onset of symptoms occurs about age 60, and about 90% of patients die within one year.

To identify the misdiagnoses of patients with sporadic Jakob-Creutzfeldt disease (sCJD) during the course of their disease and determine which medical specialties saw patients with sCJD prior to the correct diagnosis being made and at what point in the disease course a correct diagnosis was made. Retrospective medical record review.

Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, fatal brain disorder. CJD is believed to be caused by a rare type of self-replicating protein called a prion, either through gene mutation or external in

克-雅脑病 (Creutzfeldt-Jakob disease， CJD)是指由朊蛋白感染而表现为精神障碍、 痴呆、 帕金森样表现、 共济失调、 肌阵挛、 肌肉萎缩等的慢性、 进展性疾病， 又称为皮质-纹状体-脊髓变性 (corticostriatal-spinal degeneration)， 亚急性海绵状脑病 (subacute spongiform encephalopathy)， 传递性海绵状脑病 (transmissible spongiform encephalopathy)、 传递性病毒性痴呆 (transmissible virus dementia)。 本病好发于50～70岁人群， 男女均可发病， CJD受感 …

按照cjd的临床诊断标准 ，出院时分别诊断为很可能cjd和可能cjd的患者入组，对患者一般资料、临床表现及mri的特征进行总结。比较mri阳性组与阴性组、单纯皮质受累组与皮质基底节同时受累组临床特征的差异。

克-雅病（Creutzfeldt-Jakob disease），既往又称为亚急性海绵状脑病或皮质-纹状体-脊髓变性，是一种罕见的致命性中枢神经系统退行性疾病。 1920年和1921年分别由Creutzfeldt和Jakob首先报告 [ 1 , 2 ] ，并由此而命名。