EtOH/ H2O (3:2), room tem. is a class of click chemistry labeling reagents. DBCO group can exclusively react with azide-tagged mol. cules or biomolecules to form a stable triazole. The click chemistry is also known as strain promoted alkyne-azide cycloaddition (SPAAC), DBCO reagent has become widely used .

DBCO reagent is a class of click chemistry labeling reagents containing a very reactive DBCO ( (Dibenzocyclooctyne) group, DBCO reagent can react with azide-tagged molecules or biomolecules via copper-free Click Chemistry. DBCO click chemistry can be run in aqueous buffer or in organic solvents depending on the property of the substrate molecules.

DBCO, or dibenzylcyclooctyne, is a cyclic alkyne featuring a structure that allows it to participate in ‘click’ chemistry reactions. It allows for selective attachment to various functional groups, thus simplifying the complex world of bioconjugation.

Dibenzocyclooctyne-amine (DBCO-NH2), is a heterobifunctional linker containing a DBCO moiety commonly used for the site-specific functionalization of nanobodies, enabling the addition of reactive DBCO groups for subsequent click chemistry reactions. [1] Linker to link azide-containing functional groups.

2023年2月23日 · DBCO (二苯并环辛炔, Dibenzocyclooctyne) 试剂是用于应变促进的炔叠氮化物环加成（SPAAC）的最具反应性的环炔之一，可实现无铜点击化学。 通常利用多肽中的氨基，巯基或羧基，把DBCO连接到多肽上， DBCO用于无需铜离子催化的叠氮-炔环加成 (SPAAC) 反应，该反应的二级反应动力学常数可达到 1。 DBCO 系列产品包括可用于进一步连接的 DBCO-acid …

DBCO-Cy3 (DBCO-Sulfo-Cy3) 是 Cyanine3 fluorophore 的衍生物，是一种 pH (4-10) 不敏感的橙红色荧光染料 (orange fluorescent dye)，激发波长和发射波长分别为 555 nm 和 580nm。 Sulfo-Cy3 DBCO 反应动力学快，稳定性好，可用于多种标准荧光仪器。 DBCO-Cy3 是一种点击化学试剂。 它含有 DBCO 基团，可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环 …

Our SPAAC conjugation chemistry is based on the reaction of a dibenzylcyclooctyne (DBCO, also known as ADIBO (= Azadibenzocyclooctyne) or DIBAC (= Dibenzoazacyclooctyne)). This „click reaction“ is very fast at room temperature, does not require a cytotoxic Cu(I) catalyst and yields almost quantitative and stable triazoles.

2019年11月12日 · The synthesis of 4- [11,12-didehydrodibenzo [b, f]azocin-5 (6 H)-yl]-4-oxobutanoic acid, also known as dibenzoazacyclooctyne (DBCO) or aza-dibenzocyclooctyne (ADIBO), was optimized for large-scale preparations of at least 10 g with an overall yield of 42%.

11,12-Didehydro-gamma-oxodibenz [b,f]azocine-5 (6H)-butanoic acid | C19H15NO3 | CID 91757805 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

This azadibenzocyclooctyne-cyanine dye derivative is a versatile labeling reagent for detection of azide containing molecules or compounds.