Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy
2022年6月22日 · One common cause of heart failure, dilated cardiomyopathy (DCM), manifests as dilation of the left ventricle (LV) with systolic dysfunction but normal LV thickness 5. …
Shared genetic pathways contribute to risk of hypertrophic and …
2021年1月25日 · We show strong genetic correlations between LV traits and cardiomyopathies, with opposing effects in HCM and DCM. Two-sample Mendelian randomization supports a …
Nature｜单细胞核测序技术揭示心肌病转录图谱 - 腾讯网
2023年1月9日 · 扩张型心肌病（Dilated cardiomyopathy, DCM）和肥厚型心肌病（Hypertrophic cardiomyopathy, HCM）都是心衰的病因，二者至终末期均可发展为心衰，带来严重的公共健康 …
Dilated vs. Hypertrophic Cardiomyopathy - HealthCentral
2024年5月30日 · Both dilated and hypertrophic cardiomyopathy restrict the pumping of blood in the body. A key difference between these types of cardiomyopathy is whether the ventricle …
SHaRe – SHaRe Project
The goal of SHaRe, a first-of-its-kind effort, is to advance the understanding of Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM), and Arrhythmogenic …
Hypertrophic and Dilated Cardiomyopathy: Four Decades of …
Associated with HCM and DCM worldwide are heart failure, arrhythmias, and sudden cardiac death at any age. This review focuses on HCM and DCM resulting from single residue …
单细胞研究揭示心力衰竭相关细胞类型，心脏FFPE样本单细胞研究 …
通过细胞类型标记基因的基因集富集分析（GSEA）发现，成纤维细胞和内皮细胞（EC）的标记基因在DCM和ICM中显著上调，表明两类细胞的功能障碍可能与DCM和ICM有关。 此外，树突 …
肥厚型心肌病的基因学和临床诊断现状与鉴别 - 知乎
肥厚型心肌病 (hypertrophic cardiomyopathy，HCM)是一类最常见的 单基因常染色体显性遗传 性心肌病，也是青少年运动性猝死的最常见病因。HCM以不明原因的心室对称性或非对称性肥 …
肥大型心筋症（HCM）、拡張型心筋症（DCM）
心不全とは、体中の組織が求める血液を、心臓が十分に供給できないために、息切れやむくみ、全身の臓器不全などが起こり、だんだん悪くなり、生命を縮める病態のことです。 心臓を …
Nature|单细胞核测序技术揭示心肌病转录图谱 - CSDN博客
2023年1月9日 · 扩张型心肌病（Dilated cardiomyopathy, DCM）和肥厚型心肌病（Hypertrophic cardiomyopathy, HCM）都是心衰的病因，二者至终末期均可发展为心衰，带来严重的公共健康 …