ATP-dependent RNA helicase DDX3X is an enzyme that in humans is encoded by the DDX3X gene. [5][6][7] DEAD box proteins are putative RNA helicases characterized by the conserved …

DDX3 helicase is required to facilitate both the Rev-mediated export of unspliced/partially spliced human immunodeficiency virus (HIV) RNA from nucleus and Tat-dependent translation of viral …

2021年2月24日 · In this review, we describe the function of DDX3X in RNA metabolism, cellular stress response, innate immune response, metabolic stress response in pancreatic β cells and …

2021年6月3日 · DDX3 is a cellular ATP-dependent RNA helicase involved in different aspects of RNA metabolism ranging from transcription to translation and therefore, DDX3 participates in …

DDX3 属于 DEAD-box 蛋白，这是一个大的 RNA 解旋酶家族，参与细胞过程的各个方面，如细胞周期进程、细胞凋亡、先天免疫反应、病毒复制和肿瘤发生。 DDX3在不同病毒的生命周期中 …

DDX3X plays a role in many cellular and viral processes. Elucidating how the different DDX3X domains function in complex formation with RNA provides insight in the DDX3X structure and …

2021年2月24日 · In this review, we describe the function of DDX3X in RNA metabolism, cellular stress response, innate immune response, metabolic stress response in pancreatic β cells and …

2019年9月18日 · DDX3X是一种酶，当发生突变时，参与多种癌症的产生，比如 乳腺癌 、肺癌和脑癌，包括成神经管细胞瘤，即一种最为常见的恶性儿童脑瘤。 DDX3X突变也与DDX3X综合 …

DDX3 is required for hepatitis C virus (HCV) RNA replication and its expression is downregulated in hepatitis B virus (HBV) associated hepatocellular carcinoma (HCC). May function as a …

For DDX3, it exerts its multifaceted roles in viral manipulation, stress response, hypoxia, radiation response and apoptosis, and is closely related to cancer development and progression. DDX3 …