Tau/DDX6 interaction increases microRNA activity - PubMed
We found that Tau interacts with DDX6, a DEAD box RNA helicase involved in translation repression and mRNA decay as well as in the miRNA pathway. Our results demonstrate that …
Tau/DDX6 interaction increases microRNA activity
2018年8月1日 · We found that Tau interacts with DDX6, a DEAD box RNA helicase involved in translation repression and mRNA decay as well as in the miRNA pathway. Our results …
Tau/DDX6 interaction increases microRNA activity
2018年8月1日 · We found that Tau interacts with DDX6, a DEAD box RNA helicase involved in translation repression and mRNA decay as well as in the miRNA pathway. Our results …
Emerging Connections Between Tau and Nucleic Acids
2020年2月25日 · The Tau/DDX6 interaction increased the translation repression by miRNAs. Importantly, tau mutations (P301S, P301L) found in the inherited tauopathies, frontotemporal …
Human DDX6 regulates translation and decay of inefficiently
2024年7月11日 · Using ribosome profiling and RNA sequencing, we identified two classes of endogenous mRNAs that are regulated in a DDX6-dependent manner. The identified targets …
Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6
2017年2月20日 · DDX6 is a conserved DEAD-box protein (DBP) that plays central roles in cytoplasmic RNA regulation, including processing body (P-body) assembly, mRNA decapping, …
1656 - Gene ResultDDX6 DEAD-box helicase 6 [ (human)]
Identification of the DEAD box RNA helicase DDX6 as a new partner that acts in cooperation with Tau to increase miRNA activity. DDX6 modulates interaction of miR-122 with the 5' …
Tau / DDX6相互作用增加了microRNA活性。,Biochimica et …
我们发现Tau与DDX6（一种参与翻译抑制和mRNA衰减以及miRNA途径的DEAD盒RNA解旋酶）相互作用。 我们的结果表明，Tau通过DDX6增加了miRNA let-7a，miR-21和miR-124的沉默活 …
胡红雨组揭示Ataxin-2蛋白通过募集RNA解旋酶DDX6影响细胞P-bo…
2024年6月28日 · PolyQ 延伸突变的 Atx2 在细胞中发生错误折叠形成积聚物，该积聚物募集细胞质中的 DDX6，导致细胞中可溶性 DDX6 的减少。 DDX6 量的减少损坏了细胞质中 P-body 的组 …
DDX家族与天然抗病毒免疫的相关研究进展 - 道客巴巴
2020年5月18日 · DDX6DDX6 被报道参与了 HIV 病毒在细胞中的蛋白外壳组装，研究表明 DDX6 的敲除可一定程度抑制 HIV-1 对人原代 T 细胞的感染，这可能是由于 DDX6 作为一种辅助蛋 …
- 某些结果已被删除